c-Rel 抗体 (Middle Region)
Quick Overview for c-Rel 抗体 (Middle Region) (ABIN3043314)
抗原
See all c-Rel 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 268-306, Middle Region
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原理
- Anti-c-Rel Antibody Picoband®
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序列
- DQEVSESMDF RYLPDEKDAY GNKSKKQKTT LIFQKLLQD
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-c-Rel Antibody Picoband® (ABIN3043314). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of mouse c-Rel, different from the related human sequence by four amino acids.
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亚型
- IgG
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anti-REL proto-oncogene (c-Rel) (pSer503) antibody
c-Rel 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-REL proto-oncogene (c-Rel) (AA 491-540) antibodyc-Rel 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-REL proto-oncogene (c-Rel) antibodyc-Rel 适用: 人, 小鼠 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 1E7 unconjugated
anti-REL proto-oncogene (c-Rel) (AA 1-300) antibodyc-Rel 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-REL proto-oncogene (c-Rel) (Internal Region) antibodyVerified c-Rel 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-REL proto-oncogene (c-Rel) antibodyc-Rel 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 8C2 unconjugated
anti-REL proto-oncogene (c-Rel) (AA 1-209) antibodyc-Rel 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-REL proto-oncogene (c-Rel) (C-Term) antibodyc-Rel 适用: 人, 犬, 马, 兔 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-REL proto-oncogene (c-Rel) (Thr69) antibodyc-Rel 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
1. Belguise, K., Sonenshein, G. E. PKC-theta promotes c-Rel-driven mammary tumorigenesis in mice and humans by repressing estrogen receptor-alpha synthesis. J. Clin. Invest. 117: 4009-4021, 2007. 2. Gilmore TD, Kalaitzidis D, Liang MC, Starczynowski DT (March 2004). "The c-Rel transcription factor and B-cell proliferation: a deal with the devil". Oncogene 23 (13): 2275-86. 3. Ruben SM, Klement JF, Coleman TA, Maher M, Chen CH, Rosen CA (Jun 1992). "I-Rel: a novel rel-related protein that inhibits NF-kappa B transcriptional activity". Genes Dev 6 (5): 745-60. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- c-Rel (REL proto-oncogene (c-Rel))
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别名
- Rel
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背景
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Synonyms: Proto-oncogene c-Rel,Rel,
Tissue Specificity: Ubiquitously expressed, with highest levels in skeletal muscle, heart and thymus. Overexpressed in prostate tumor tissue. .
Background: The proto-oncogene c-Rel is a protein that in humans is encoded by the REL gene. This gene is mapped to chromosome 2p13-p12. The c-Rel protein is a member of the NF-κB family of transcription factors and contains a Rel homology domain (RHD) at its N-terminus and two C-terminal transactivation domains. c-Rel has an important role in B-cell survival and proliferation. The REL gene is amplified or mutated in several human B-cell lymphomas, including diffuse large B-cell lymphoma and Hodgkin's lymphoma.
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分子量
- 69 kDa
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基因ID
- 19696
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UniProt
- P15307
抗原
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