IKK alpha 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for IKK alpha 抗体 (C-Term) (ABIN3043147)
抗原
See all IKK alpha (CHUK) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 728-745, C-Term
-
原理
- Anti-IKK alpha/CHUK Antibody
-
序列
- NEEQGNSMMN LDWSWLTE
-
交叉反应 （详细）
- No cross-reactivity with other proteins
-
产品特性
- Anti-IKK alpha/CHUK Antibody (ABIN3043147). Tested in Flow Cytometry, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human IKK alpha.
-
亚型
- IgG
-
-
anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (C-Term) antibody
CHUK 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (pSer176), (pSer177) antibodyCHUK 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (AA 646-745) antibodyCHUK 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4B8 unconjugated
anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (pThr23) antibodyCHUK 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (AA 646-745) antibodyCHUK 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 1F8 unconjugated
anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) antibodyCHUK 适用: 人 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 3G12H9 unconjugated
anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (AA 411-745) antibodyCHUK 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (pThr23) antibodyCHUK 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) antibodyCHUK 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB2159 unconjugated
anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (N-Term) antibodyCHUK 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.1-0.5 μg/mL, Human
Flow Cytometry(Fixed), 1-3 μg/1x106 cells, Human
-
说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
-
-
- IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))
-
别名
- CHUK
-
背景
-
Synonyms: Inhibitor of nuclear factor kappa-B kinase subunit alpha,I-kappa-B kinase alpha,IKK-A,IKK-alpha,IkBKA,IkappaB kinase,2.7.11.10,Conserved helix-loop-helix ubiquitous kinase,I-kappa-B kinase 1,IKK1,Nuclear factor NF-kappa-B inhibitor kinase alpha,NFKBIKA,Transcription factor 16,TCF-16,CHUK,IKKA, TCF16,
Tissue Specificity: Widely expressed.
Background: IKBKA (INHIBITOR OF KAPPA LIGHT POLYPEPTIDE GENE ENHANCER IN B CELLS, KINASE OF, ALPHA), also called CHUK, NFKBIKA, IKKA, IKK1, I-KAPPA-B, is a protein kinase that in humans is encoded by the CHUK gene. And it is a member of the protein kinase superfamily. And the protein contains a serine/threonine kinase domain, due to its ubiquitous expression in a broad array of tissues and high degree of conservation across species. By FISH, the IKBKA gene is mapped to chromosome 10q24. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. IKK-alpha is part of the I kappa B kinase complex that plays an important role in regulating the NF-kappa B transcription factor.
Sequence Similarities: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily.
-
分子量
- 85 kDa
-
UniProt
- O15111
-
途径
- PI3K-Akt Signaling, NF-kappaB Signaling, RTK signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
抗原
-
