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SPTLC1 抗体 (Middle Region)

SPTLC1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043056
发货至: 中国
  • 抗原 See all SPTLC1 抗体
    SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))
    抗原表位
    • 15
    • 7
    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 138-154, Middle Region
    适用
    • 54
    • 20
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 54
    • 1
    克隆类型
    • 54
    • 1
    多克隆
    标记
    • 24
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This SPTLC1 antibody is un-conjugated
    应用范围
    • 48
    • 21
    • 13
    • 13
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Serine palmitoyltransferase 1(SPTLC1) detection. Tested with WB, IHC-P in Human.
    序列
    FYGTFDVHLD LEDRLAK
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Serine palmitoyltransferase 1(SPTLC1) detection. Tested with WB, IHC-P in Human.
    Gene Name: serine palmitoyltransferase, long chain base subunit 1
    Protein Name: Serine palmitoyltransferase 1
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence in the middle region of human SPTLC1(138-154aa FYGTFDVHLDLEDRLAK).
    亚型
    IgG
    Top Product
    Discover our top product SPTLC1 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • 抗原
    SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))
    别名
    SPTLC1 (SPTLC1 产品)
    别名
    ATSPT1 antibody, SERINE PALMITOYLTRANSFERASE 1 antibody, serine palmitoyltransferase 1 antibody, Afu6g00300 antibody, HSAN1 antibody, HSN1 antibody, LBC1 antibody, LCB1 antibody, SPT1 antibody, SPTI antibody, wu:fc75h04 antibody, wu:fp41c08 antibody, zgc:112247 antibody, AW552086 antibody, C77762 antibody, E030036H05 antibody, Lcb1 antibody, RGD1306617 antibody, Spt1 antibody, serine palmitoyltransferase 1 antibody, Serine palmitoyltransferase 1 antibody, serine palmitoyltransferase long chain base subunit 1 antibody, serine palmitoyltransferase, long chain base subunit 1 antibody, serine palmitoyltransferase, long chain base subunit 1 L homeolog antibody, SPT1 antibody, AFUA_6G00300 antibody, PAS_FragB_0040 antibody, SPTLC1 antibody, sptlc1 antibody, sptlc1.L antibody, Sptlc1 antibody
    背景
    SPTLC1(Serine palmitoyltransferase, long chain base subunit 1), also known as SPT1, LCB1, is a protein which in humans is encoded by the SPTLC1 gene. Dawkins et al.(2001)noted that the SPTLC1 gene maps to chromosome 9q22.1-q22.3. Serine palmitoyltransferase, which consists of two different subunits, is the initial enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. The product of this gene is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified.

    Synonyms: HSAN antibody|HSAN1 antibody|HSN1 antibody|LBC1 antibody|LCB 1 antibody|LCB1 antibody|Long chain base biosynthesis protein 1 antibody|MGC14645 antibody|Serine C palmitoyltransferase antibody|Serine palmitoyl CoA transferase 1 antibody|Serine palmitoyltransferase 1 antibody|Serine palmitoyltransferase long chain base subunit 1 antibody|Serine palmitoyltransferase subunit 1 antibody|Serine-palmitoyl-CoA transferase 1 antibody|SPT 1 antibody|SPT1 antibody|SPTC1_HUMAN antibody|SPTI antibody|SPTLC 1 antibody|SPTLC1 antibody
    UniProt
    O15269
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