-
- 抗原 See all PCSK4 抗体
- PCSK4 (Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4))
-
抗原表位
- AA 117-133, N-Term
-
适用
- 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This PCSK4 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for Proprotein convertase subtilisin/kexin type 4(PCSK4) detection. Tested with WB in Mouse,Rat.
- 序列
- DPWFSKQWYM NKEIQQD
- 交叉反应 （详细）
-
Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
-
Rabbit IgG polyclonal antibody for Proprotein convertase subtilisin/kexin type 4(PCSK4) detection. Tested with WB in Mouse,Rat.
Gene Name: proprotein convertase subtilisin/kexin type 4
Protein Name: Proprotein convertase subtilisin/kexin type 4 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of mouse Proprotein convertase PC4(117-133aa DPWFSKQWYMNKEIQQD), different from the related rat sequence by one amino acid.
- 亚型
- IgG
- Top Product
- Discover our top product PCSK4 Primary Antibody
-
anti-Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4) (AA 1-242) antibody
PCSK4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4) (AA 35-84) antibodyPCSK4 适用: 人, 小鼠, 大鼠, Cow, 犬, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4) (AA 168-196) antibodyPCSK4 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4) (N-Term) antibodyPCSK4 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
-
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
-
- 抗原
- PCSK4 (Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4))
- 别名
- PCSK4 (PCSK4 产品)
- 别名
- PC4 antibody, SPC5 antibody, AI647044 antibody, L21221 antibody, NEC 3 antibody, NEC3 antibody, PCSK4 antibody, pc4 antibody, spc5 antibody, MGC146505 antibody, pcsk4 antibody, proprotein convertase subtilisin/kexin type 4 antibody, proprotein convertase subtilisin/kexin type 4 L homeolog antibody, PCSK4 antibody, Pcsk4 antibody, pcsk4 antibody, pcsk4.L antibody
- 背景
-
PCSK4(Proprotein Convertase, Subtilisin/Kexin-Type, 4), is an enzyme that in humans is encoded by the PCSK4 gene. The gene for PC4(Pcsk4 locus) was mapped to mouse chromosome 10, close to the adipsin locus and near the gene encoding anti-mullerian hormone. Qiu et al.(2005) found that aberrant processing of pro-IGF2 by PC4 may be a cause of IUGR. PC4 cleaved pro-IGF2 to generate the intermediate processed form, IGF2(1-102). Mature IGF2(1-67), likely resulting from further processing by carboxypeptidases, is capable of activating invasive trophoblast cells through AKT phosphorylation. Inhibition of PC4 by a PC4-specific inhibitor blocked pro-IGF2 processing and reduced trophoblast cell migration.
Synonyms: PC4 antibody|PCSK4 antibody|PCSK4_HUMAN antibody|Proprotein convertase 4 antibody|Proprotein convertase PC4 antibody|Proprotein convertase subtilisin/kexin type 4 antibody|SPC5 antibody - UniProt
- P29121
-
You are here:
