-
- 抗原 See all PCSK4 抗体
- PCSK4 (Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4))
-
抗原表位
- N-Term
-
适用
- 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This PCSK4 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 纯化方法
- Antigen affinity
- 免疫原
- An amino acid sequence from the N-terminus of mouse Proprotein convertase 4 (DPWFSKQWYMNKEIQQD) was used as the immunogen for this Proprotein Convertase 4 antibody.
- 亚型
- IgG
- Top Product
- Discover our top product PCSK4 Primary Antibody
-
anti-Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4) (AA 1-242) antibody
PCSK4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4) (AA 35-84) antibodyPCSK4 适用: 人, 小鼠, 大鼠, Cow, 犬, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4) (AA 168-196) antibodyPCSK4 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- The stated application concentrations are suggested starting amounts. Titration of the Proprotein Convertase 4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
- 限制
- 仅限研究用
-
- 缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- 储存条件
- -20 °C
- 储存方法
- After reconstitution, the Proprotein Convertase 4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
-
- 抗原
- PCSK4 (Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4))
- 别名
- Proprotein Convertase 4 (PCSK4 产品)
- 别名
- PC4 antibody, SPC5 antibody, AI647044 antibody, L21221 antibody, NEC 3 antibody, NEC3 antibody, PCSK4 antibody, pc4 antibody, spc5 antibody, MGC146505 antibody, pcsk4 antibody, proprotein convertase subtilisin/kexin type 4 antibody, proprotein convertase subtilisin/kexin type 4 L homeolog antibody, PCSK4 antibody, Pcsk4 antibody, pcsk4 antibody, pcsk4.L antibody
- 背景
- Proprotein Convertase, Subtilisin/Kexin-Type, 4, is an enzyme that in humans is encoded by the PCSK4 gene. The gene was mapped to mouse chromosome 10, close to the adipsin locus and near the gene encoding anti-mullerian hormone. Qiu et al.(2005) found that aberrant processing of pro-IGF2 may be a cause of IUGR. PCSK4 cleaved pro-IGF2 to generate the intermediate processed form, IGF2(1-102). Mature IGF2(1-67), likely resulting from further processing by carboxypeptidases, is capable of activating invasive trophoblast cells through AKT phosphorylation. Inhibition of the protein by a PCSK4-specific inhibitor blocked pro-IGF2 processing and reduced trophoblast cell migration.
- UniProt
- P29121
-
You are here:
