-
- 抗原 See all CYP7A1 抗体
- CYP7A1 (Cytochrome P450, Family 7, Subfamily A, Polypeptide 1 (CYP7A1))
-
抗原表位
- AA 301-504
-
适用
- 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This CYP7A1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for Cholesterol 7-alpha-monooxygenase(CYP7A1) detection. Tested with WB in Human,Mouse,Rat.
- 交叉反应 （详细）
-
Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
-
Rabbit IgG polyclonal antibody for Cholesterol 7-alpha-monooxygenase(CYP7A1) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: cytochrome P450, family 7, subfamily A, polypeptide 1
Protein Name: Cholesterol 7-alpha-monooxygenase - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human CYP7A1 recombinant protein (Position: M301-L504). Human CYP7A1 shares 85.2 % and 83.3% amino acid (aa) sequence identity with mouse and rat CYP7A1, respectively.
- 亚型
- IgG
- Top Product
- Discover our top product CYP7A1 Primary Antibody
-
anti-Cytochrome P450, Family 7, Subfamily A, Polypeptide 1 (CYP7A1) (AA 351-400) antibody
CYP7A1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (p), IF (cc), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 7, Subfamily A, Polypeptide 1 (CYP7A1) (AA 227-467) antibodyCYP7A1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 7, Subfamily A, Polypeptide 1 (CYP7A1) (AA 303-423) antibodyCYP7A1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 7, Subfamily A, Polypeptide 1 (CYP7A1) (AA 179-277) antibodyCYP7A1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8F1 unconjugated
anti-Cytochrome P450, Family 7, Subfamily A, Polypeptide 1 (CYP7A1) (Internal Region) antibodyCYP7A1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 7, Subfamily A, Polypeptide 1 (CYP7A1) (AA 109-383) antibodyCYP7A1 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 7, Subfamily A, Polypeptide 1 (CYP7A1) antibodyCYP7A1 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 7, Subfamily A, Polypeptide 1 (CYP7A1) (AA 27-58), (N-Term) antibodyCYP7A1 适用: 人 WB 宿主: 兔 Polyclonal RB52160 unconjugated
anti-Cytochrome P450, Family 7, Subfamily A, Polypeptide 1 (CYP7A1) (AA 476-504), (C-Term) antibodyCYP7A1 适用: 人 WB 宿主: 兔 Polyclonal RB17086 unconjugated
-
- 应用备注
-
WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
-
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
-
- 抗原
- CYP7A1 (Cytochrome P450, Family 7, Subfamily A, Polypeptide 1 (CYP7A1))
- 别名
- CYP7A1 (CYP7A1 产品)
- 别名
- CP7A antibody, CYP7 antibody, CYPVII antibody, CHAP antibody, CYP7S1 antibody, cyp7a1a antibody, zgc:63920 antibody, cytochrome P450 family 7 subfamily A member 1 antibody, cytochrome P450, family 7, subfamily a, polypeptide 1 antibody, cytochrome P450, family 7, subfamily A, polypeptide 1 antibody, cholesterol 7-alpha-hydroxylase antibody, CYP7A1 antibody, Cyp7a1 antibody, cyp7a1 antibody
- 背景
-
CYP7A1 (Cytochrome P450 Subfamily VIIA Polypeptide 1), also called CYP7 or CHOLESTEROL 7-ALPHA -HYDROXYLASE, is an enzyme that in humans is encoded by the CYP7A1 gene. Using both mouse-human somatic cell hybrids and in situ chromosomal hybridization, Cohen et al. (1992) mapped the CYP7 gene to 8q11-q12. By transfection of reporter constructs, mutation analysis, and DNase footprinting, Molowa et al. (1992) identified areas of the CYP7A1 promoter region that showed hepatocyte-specific activation. They found HNF3 to be an activator of CYP7A1 activity. Agellon et al. (2002) found that wildtype mice and mice transgenic for human CYP7A1 respond differently to cholesterol feeding. Cholesterol feeding stimulated Cyp7a1 mRNA abundance and enzymatic activity in wildtype mice, but repressed human CYP7A1 mRNA and activity in transgenic mice.
Synonyms: Cholesterol 7 alpha hydroxylase antibody|Cholesterol 7 alpha monooxygenase antibody| cholesterol 7 alpha-monooxygenase antibody|Cholesterol 7-alpha-hydroxylase antibody| Cholesterol 7-alpha-monooxygenase antibody|CP7A antibody|CP7A1_HUMAN antibody|CYP 7 antibody|CYP7 antibody|CYP7A1 antibody|CYPVII antibody|Cytochrome P450 7A1 antibody| cytochrome P450, family 7, subfamily A, polypeptide 1 antibody|Cytochrome P450, subfamily VIIA (cholesterol 7 alpha monooxygenase), antibody|cytochrome P450, subfamily VIIA (cholesterol 7 alpha-monooxygenase), antibody|Cytochrome P450, subfamily VIIA (cholesterol 7 alpha-monooxygenase), polypeptide 1 antibody|MGC126826 antibody|MGC138389 antibody - 基因ID
- 1581
- UniProt
- P22680
- 途径
- Steroid Hormone Biosynthesis, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha
-
You are here:
