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Involucrin 抗体 (C-Term)

IVL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042470
发货至: 中国
  • 抗原 See all Involucrin (IVL) 抗体
    Involucrin (IVL)
    抗原表位
    • 15
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 551-585, C-Term
    适用
    • 87
    • 24
    • 23
    • 17
    • 17
    • 10
    • 9
    • 8
    • 5
    • 2
    宿主
    • 59
    • 36
    克隆类型
    • 49
    • 46
    多克隆
    标记
    • 44
    • 10
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Involucrin antibody is un-conjugated
    应用范围
    • 33
    • 32
    • 27
    • 25
    • 23
    • 21
    • 19
    • 15
    • 13
    • 13
    • 11
    • 9
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Involucrin(IVL) detection. Tested with WB in Human.
    序列
    QVQDIQPALP TKGEVLLPVE HQQQKQEVQW PPKHK
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Involucrin(IVL) detection. Tested with WB in Human.
    Gene Name: involucrin
    Protein Name: Involucrin
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human Involucrin (551-585aa QVQDIQPALPTKGEVLLPVEHQQQKQEVQWPPKHK).
    亚型
    IgG
    Top Product
    Discover our top product IVL Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    Involucrin (IVL)
    别名
    IVL (IVL 产品)
    别名
    INV antibody, NPH2 antibody, NPHP2 antibody, 1110019C06Rik antibody, IVL antibody, Nphp2 antibody, inv antibody, involucrin antibody, inversin antibody, IVL antibody, INVS antibody, Ivl antibody, Invs antibody
    背景
    Involucrin is a protein component of human skin and in humans is encoded by the IVL gene. It is a highly reactive, soluble, transglutaminase substrate protein present in keratinocytes of epidermisand other stratified squamous epithelia. It first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase thus helping in the formation of an insoluble envelope beneath theplasma membrane functioning as a glutamyl donor during assembly of the cornified envelope. Additionally, Involucrin is synthesised in the stratum spinosum and cross linked in the stratum granulosum by thetransglutaminase enzyme that makes it highly stable. Thus it provides structural support to the cell, thereby allowing the cell to resist invasion by micro-organisms.

    Synonyms: INVO_HUMAN antibody|Involucrin antibody|IVL antibody
    基因ID
    3713
    UniProt
    P07476
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