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HMOX1 抗体 (AA 1-288)

Name: HMOX1 抗体 (AA 1-288)
SKU: ABIN3042449
Availability: OutOfStock

HMOX1 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

Anti- HMOX1 antibody, Western blotting All lanes: Anti HMOX1 at 0. (HMOX1 抗体 (AA 1-288))

Anti- HMOX1 antibody, IHC(P) IHC(P): Human Lung Cancer Tissue (HMOX1 抗体 (AA 1-288))

IHC

3 images

(18 references)

产品编号 ABIN3042449

发货至: 中国

Datasheet as PDF

抗原 See all HMOX1 抗体

HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))
抗原表位
12

7

7

7

6

6

6

6

6

5

5

4

3

3

3

2

2

2

1

1

1

1

1

1

1
AA 1-288
适用
113

60

43

15

11

9

8

8

7

5

2

2

2

2

2
人, 大鼠
宿主
120

43

2

1

1
兔
Compatible Secondaries
克隆类型
117

50
多克隆
标记
74

20

16

9

8

8

6

4

4

4

2

2

2

2

2

2

2
This HMOX1 antibody is un-conjugated
应用范围
139

76

54

51

49

37

22

8

5

3

3

2

2

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

原理

Rabbit IgG polyclonal antibody for Heme oxygenase 1(HMOX1) detection. Tested with WB, IHC-P in Human,Rat.

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for Heme oxygenase 1(HMOX1) detection. Tested with WB, IHC-P in Human,Rat.
Gene Name: heme oxygenase (decycling) 1
Protein Name: Heme oxygenase 1

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human HMOX1 recombinant protein (Position: M1-M288). Human HMOX1 shares 82% and 80% amino acid (aa) sequences identity with mouse and rat HMOX1, respectively.

亚型

IgG

Top Product

Discover our top product HMOX1 Primary Antibody
anti-Heme Oxygenase (Decycling) 1 (HMOX1) antibody
KO Validated HMOX1 适用: 人 WB, ELISA, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Heme Oxygenase (Decycling) 1 (HMOX1) (AA 1-288) antibody
HMOX1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Heme Oxygenase (Decycling) 1 (HMOX1) (AA 1-30) antibody
HMOX1 适用: 人 WB, IHC, IP, ELISA, ICC, IF 宿主: 小鼠 Monoclonal 1F12-A6 unconjugated

anti-Heme Oxygenase (Decycling) 1 (HMOX1) antibody
HMOX1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated

anti-Heme Oxygenase (Decycling) 1 (HMOX1) (AA 1-30) antibody (HRP)
HMOX1 适用: 人 WB, IHC, IP, ELISA, ICC, IF 宿主: 小鼠 Monoclonal 1F12-A6 HRP

anti-Heme Oxygenase (Decycling) 1 (HMOX1) (N-Term) antibody
HMOX1 适用: 人, 大鼠, 小鼠, Pig, 犬, Cow, 兔, 豚鼠, 山羊 WB 宿主: 兔 Polyclonal unconjugated

anti-Heme Oxygenase (Decycling) 1 (HMOX1) (AA 99-237) antibody
HMOX1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Heme Oxygenase (Decycling) 1 (HMOX1) (AA 61-172) antibody
HMOX1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal A4 unconjugated

anti-Heme Oxygenase (Decycling) 1 (HMOX1) (AA 61-172) antibody
HMOX1 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Heme Oxygenase (Decycling) 1 (HMOX1) (AA 1-30) antibody (FITC)
HMOX1 适用: 人 WB, IHC, IP, ELISA, ICC, IF 宿主: 小鼠 Monoclonal 1F12-A6 FITC

应用备注

WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, The detection limit for HMOX1 is approximately 0.2 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Wei, Kong, Li, Guan, Wang, Miao: "Nicotinamide mononucleotide attenuates brain injury after intracerebral hemorrhage by activating Nrf2/HO-1 signaling pathway." in: Scientific reports, Vol. 7, Issue 1, pp. 717, (2018) (PubMed).

Zhu, Chen, Chen, Yang, Xie: "Astaxanthin Promotes Nrf2/ARE Signaling to Alleviate Renal Fibronectin and Collagen IV Accumulation in Diabetic Rats." in: Journal of diabetes research, Vol. 2018, pp. 6730315, (2018) (PubMed).

Wu, Li, Cui, Wu, Hong, Li, Wu, Jie, Wang, Li: "The Natural Flavone Acacetin Confers Cardiomyocyte Protection Against Hypoxia/Reoxygenation Injury via AMPK-Mediated Activation of Nrf2 Signaling Pathway." in: Frontiers in pharmacology, Vol. 9, pp. 497, (2018) (PubMed).

Li Volti, Avola, Tibullo: "Commentary: The apolipoprotein A-I mimetic peptide, D-4F, restrains neointimal formation through heme oxygenase-1 up-regulation." in: Frontiers in pharmacology, Vol. 8, pp. 708, (2017) (PubMed).

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Chen, Wang, Li, Jiang, Lu, Zhou: "Heme Oxygenase-1 Promotes Delayed Wound Healing in Diabetic Rats." in: Journal of diabetes research, Vol. 2016, pp. 9726503, (2016) (PubMed).

Guo, Li, Duan, Wang, Zhou, Sun: "Octreotide attenuates liver fibrosis by inhibiting hepatic heme oxygenase-1 expression." in: Molecular medicine reports, Vol. 11, Issue 1, pp. 83-90, (2015) (PubMed).

Guo, Duan, Wang, Zhou, Li, Sun: "Endogenous carbon monoxide downregulates hepatic cystathionine-γ-lyase in rats with liver cirrhosis." in: Experimental and therapeutic medicine, Vol. 10, Issue 6, pp. 2039-2046, (2015) (PubMed).

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Li, Han, Li, Jiang, Wang: "Upregulation of heat shock protein 32 in Sertoli cells alleviates the impairments caused by heat shock-induced apoptosis in mouse testis." in: Cell stress & chaperones, Vol. 18, Issue 3, pp. 333-51, (2013) (PubMed).

Wang, Li, Lu, Zhao, Xu: "Taurine attenuates oxidative stress and alleviates cardiac failure in type I diabetic rats." in: Croatian medical journal, Vol. 54, Issue 2, pp. 171-9, (2013) (PubMed).

Wang, Li, Lu, Zhao: "Riboflavin alleviates cardiac failure in Type I diabetic cardiomyopathy." in: Heart international, Vol. 6, Issue 2, pp. e21, (2012) (PubMed).

Guo, Duan, Li, Sun: "Effect of heme oxygenase-1 on renal function in rats with liver cirrhosis." in: World journal of gastroenterology, Vol. 17, Issue 3, pp. 322-8, (2011) (PubMed).

Xia, Liu, Zhou, Tang, Zou: "Comparison of the effects of propofol and midazolam on inflammation and oxidase stress in children with congenital heart disease undergoing cardiac surgery." in: Yonsei medical journal, Vol. 52, Issue 2, pp. 326-32, (2011) (PubMed).

Wang, Duan, Sun: "Influence of heme oxygenase-1 expression on immune liver fibrosis induced by cobalt protoporphyrin in rats." in: World journal of gastroenterology, Vol. 15, Issue 24, pp. 3009-14, (2009) (PubMed).

Xue, Guo, Li, Hao: "Heme oxygenase-1 induction by hemin protects liver cells from ischemia/reperfusion injury in cirrhotic rats." in: World journal of gastroenterology, Vol. 13, Issue 40, pp. 5384-90, (2007) (PubMed).
抗原

HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))

别名

HMOX1 (HMOX1 产品)

别名

HMOX1 antibody, ARABIDOPSIS THALIANA HEME OXYGENASE 1 antibody, ATHO1 antibody, F18A8.4 antibody, F18A8_4 antibody, GENOMES UNCOUPLED 2 antibody, GUN2 antibody, HEME OXYGENASE antibody, HEME OXYGENASE 1 antibody, HEME OXYGENASE 6 antibody, HO1 antibody, HY1 antibody, HY6 antibody, PLASTID HEME OXYGENASE antibody, REVERSAL OF THE DET PHENOTYPE 4 antibody, HO-1 antibody, wu:fc27c04 antibody, zgc:65984 antibody, D8Wsu38e antibody, Hemox antibody, Hmox antibody, Hsp32 antibody, HEOXG antibody, Heox antibody, Ho-1 antibody, Ho1 antibody, hsp32 antibody, MGC132176 antibody, Hmox1 antibody, HMOX1D antibody, HSP32 antibody, bK286B10 antibody, heme oxygenase 1 antibody, Plant heme oxygenase (decyclizing) family protein antibody, Heme oxygenase antibody, heme oxygenase antibody, heme oxygenase 1, chloroplastic antibody, heme oxygenase 1a antibody, heme oxygenase 1 L homeolog antibody, HMOX1 antibody, TED4 antibody, ho1 antibody, P9301_RS17555 antibody, A9601_RS17590 antibody, MAE_RS06565 antibody, HO1 antibody, hmox1a antibody, CPE0214 antibody, Cyan7425_2962 antibody, Hmox1 antibody, hmox1.L antibody, AM1_C0205 antibody, CC1G_11686 antibody, CpipJ_CPIJ007246 antibody

背景

HMOX1 (heme oxygenase (decycling) 1), also known as HO-1, is a human gene that encodes for the enzyme heme oxygenase 1. It is an essential enzyme in heme catabolism, it cleaves heme to form biliverdin. HMOX1 belongs to the heme oxygenase family. The HMOX1 gene is located on the long (q) arm of chromosome 22 at position 12.3, from base pair 34,101,636 to base pair 34,114,748. HMOX1, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. HMOX1 activity is induced by its substrate heme and by various nonheme substances.

Synonyms: 32 kD antibody|bK286B10 antibody|D8Wsu38e antibody|heat shock protein 32 kD antibody|heat shock protein 32kD antibody|Heat shock protein antibody|Heme oxygenase (decycling) 1 antibody|Heme oxygenase 1 antibody|Hemox antibody|HMOX 1 antibody|Hmox antibody|HMOX1 antibody|HMOX1_HUMAN antibody|HO 1 antibody|HO antibody|HO-1 antibody|HO1 antibody|Hsp32 antibody

基因ID

3162

UniProt

P09601

途径

Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interactome