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HMOX1 抗体

KO Validated HMOX1 适用: 人 WB, ELISA, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2854952
发货至: 中国
  • 抗原 See all HMOX1 抗体
    HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))
    适用
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    宿主
    • 121
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    克隆类型
    • 117
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    多克隆
    标记
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    This HMOX1 antibody is un-conjugated
    应用范围
    • 142
    • 77
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    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 猴, 小鼠, 大鼠
    产品特性
    Rabbit Polyclonal antibody to Heme Oxygenase 1 (heme oxygenase (decycling) 1)
    Heme Oxygenase 1 antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    质量等级
    KO Validated
    免疫原
    Recombinant protein encompassing a sequence within the center region of human Heme Oxygenase 1. The exact sequence is proprietary.
    亚型
    IgG
  • 应用备注
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: Raw264.7 , C2C12

    Validation: KO/KD, Orthogonal

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.45 mg/mL
    缓冲液
    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Batubara, Astuti, Prastya, Ilmiawati, Maeda, Suzuki, Hamamoto, Takemori: "The Antiaging Effect of Active Fractions and Ent-11α-Hydroxy-15-Oxo-Kaur-16-En-19-Oic Acid Isolated from Adenostemma lavenia (L.) O. Kuntze at the Cellular Level." in: Antioxidants (Basel, Switzerland), Vol. 9, Issue 8, (2020) (PubMed).

    Neitzel, Seiwert, Göder, Diehl, Weber, Nagel, Stroh, Rasenberger, Christmann, Fahrer: "Lipoic Acid Synergizes with Antineoplastic Drugs in Colorectal Cancer by Targeting p53 for Proteasomal Degradation." in: Cells, Vol. 8, Issue 8, (2020) (PubMed).

    Tsai, Jou, Tsai, Shiau, Wu, Tzai et al.: "Prothymosin-α enhances phosphatase and tensin homolog expression and binds with tripartite motif-containing protein 21 to regulate Kelch-like ECH-associated protein 1/nuclear factor erythroid ..." in: Cancer science, Vol. 110, Issue 4, pp. 1208-1219, (2019) (PubMed).

    Yeh, Wu, Cheng, Tsai, Chang, Yeh, Wu, Lee, Chiang: "HO-1 is a favorable prognostic factor for HBV-HCC patients who underwent hepatectomy." in: Cancer management and research, Vol. 10, pp. 6049-6059, (2018) (PubMed).

    Ugun-Klusek, Tatham, Elkharaz, Constantin-Teodosiu, Lawler, Mohamed, Paine, Anderson, John Mayer, Lowe, Ellen Billett, Bedford: "Continued 26S proteasome dysfunction in mouse brain cortical neurons impairs autophagy and the Keap1-Nrf2 oxidative defence pathway." in: Cell death & disease, Vol. 8, Issue 1, pp. e2531, (2017) (PubMed).

    Xu, Wu, Zheng, Yu, Yang, Yao, Zhou, Ching, Lau: "Proteome profiling of cadmium-induced apoptosis by antibody array analyses in human bronchial epithelial cells." in: Oncotarget, Vol. 7, Issue 5, pp. 6146-58, (2017) (PubMed).

  • 抗原
    HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))
    别名
    heme oxygenase 1 (HMOX1 产品)
    别名
    HMOX1 antibody, ARABIDOPSIS THALIANA HEME OXYGENASE 1 antibody, ATHO1 antibody, F18A8.4 antibody, F18A8_4 antibody, GENOMES UNCOUPLED 2 antibody, GUN2 antibody, HEME OXYGENASE antibody, HEME OXYGENASE 1 antibody, HEME OXYGENASE 6 antibody, HO1 antibody, HY1 antibody, HY6 antibody, PLASTID HEME OXYGENASE antibody, REVERSAL OF THE DET PHENOTYPE 4 antibody, HO-1 antibody, wu:fc27c04 antibody, zgc:65984 antibody, D8Wsu38e antibody, Hemox antibody, Hmox antibody, Hsp32 antibody, HEOXG antibody, Heox antibody, Ho-1 antibody, Ho1 antibody, hsp32 antibody, MGC132176 antibody, Hmox1 antibody, HMOX1D antibody, HSP32 antibody, bK286B10 antibody, heme oxygenase 1 antibody, Plant heme oxygenase (decyclizing) family protein antibody, Heme oxygenase antibody, heme oxygenase antibody, heme oxygenase 1, chloroplastic antibody, heme oxygenase 1a antibody, heme oxygenase 1 L homeolog antibody, HMOX1 antibody, TED4 antibody, ho1 antibody, P9301_RS17555 antibody, A9601_RS17590 antibody, MAE_RS06565 antibody, HO1 antibody, hmox1a antibody, CPE0214 antibody, Cyan7425_2962 antibody, Hmox1 antibody, hmox1.L antibody, AM1_C0205 antibody, CC1G_11686 antibody, CpipJ_CPIJ007246 antibody
    背景
    Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family.

    Cellular Localization: Microsome , Endoplasmic reticulum
    分子量
    33 kDa
    基因ID
    3162
    UniProt
    P09601
    途径
    Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interactome
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