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PAR1 抗体 (N-Term)

Name: PAR1 抗体 (N-Term)
SKU: ABIN3042380
Availability: OutOfStock

F2R 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

Western Blotting (WB) image for anti-Coagulation Factor II (thrombin) Receptor (F2R) (AA 46-82), (N-Term) antibody (ABIN3042380) (PAR1 抗体 (N-Term))

Anti- Thrombin Receptor antibody, IHC(P) IHC(P): Human Placenta Tissue (PAR1 抗体 (N-Term))

IHC

2 images

产品编号 ABIN3042380

发货至: 中国

Datasheet as PDF

抗原 See all PAR1 (F2R) 抗体

PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))
抗原表位
16

15

8

7

5

4

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 46-82, N-Term
适用
69

25

23

3

2

2

2

2

2

1
人
宿主
62

7

2
兔
Compatible Secondaries
克隆类型
65

6
多克隆
标记
40

7

5

4

2

2

1

1

1

1

1

1

1

1

1

1

1
This PAR1 antibody is un-conjugated
应用范围
61

36

13

13

11

8

8

6

5

5

3

2

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

原理

Rabbit IgG polyclonal antibody for Proteinase-activated receptor 1(F2R) detection. Tested with WB, IHC-P in Human.

序列

RNPNDKYEPF WEDEEKNESG LTEYRLVSIN KSSPLQK

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for Proteinase-activated receptor 1(F2R) detection. Tested with WB, IHC-P in Human.
Gene Name: coagulation factor II (thrombin) receptor
Protein Name: Proteinase-activated receptor 1

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the N-terminus of human Thrombin Receptor (46-82aa RNPNDKYEPFWEDEEKNESGLTEYRLVSINKSSPLQK).

亚型

IgG

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anti-Coagulation Factor II (thrombin) Receptor (F2R) (AA 42-102) antibody
F2R 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 2C5 unconjugated

anti-Coagulation Factor II (thrombin) Receptor (F2R) (N-Term) antibody
F2R 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Coagulation Factor II (thrombin) Receptor (F2R) (AA 42-176) antibody
F2R 适用: 人 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 5E2E6 unconjugated

anti-Coagulation Factor II (thrombin) Receptor (F2R) (AA 61-76), (Extracellular), (N-Term) antibody
F2R 适用: 人 WB, IHC, FACS, ICC, IF, LCI 宿主: 兔 Polyclonal unconjugated

anti-Coagulation Factor II (thrombin) Receptor (F2R) (AA 42-102) antibody
F2R 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Coagulation Factor II (thrombin) Receptor (F2R) antibody
F2R 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Coagulation Factor II (thrombin) Receptor (F2R) (AA 1-425) antibody
F2R 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated

anti-Coagulation Factor II (thrombin) Receptor (F2R) (Internal Region) antibody
Verified F2R 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Coagulation Factor II (thrombin) Receptor (F2R) (AA 267-316) antibody
F2R 适用: 人, 大鼠, 小鼠, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated

应用备注

WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
抗原

PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))

别名

F2R (F2R 产品)

别名

CF2R antibody, HTR antibody, PAR-1 antibody, PAR1 antibody, TR antibody, Par1 antibody, TRGPC antibody, AI482343 antibody, Cf2r antibody, ThrR antibody, Par-1 antibody, f2r-a antibody, par1 antibody, coagulation factor II thrombin receptor antibody, coagulation factor II (thrombin) receptor antibody, coagulation factor 2 (thrombin) receptor L homeolog antibody, F2R antibody, F2r antibody, f2r.L antibody

背景

Proteinase-activated receptor 1 (PAR1), also known as the coagulation factor II (thrombin) receptor, is a protein that in humans is encoded by the F2R gene. By fluorescence in situ hybridization, this gene is mapped to 5q13, confirming its presence as a single locus in the human genome. PAR1 is a G protein-coupled receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. The expression of PAR1 is both required and sufficient to promote growth and invasion of breast carcinoma cells in a xenograft mouse model.

Synonyms: CF2R antibody|Coagulation factor II (thrombin) receptor antibody|Coagulation factor II receptor antibody|F2R antibody|HTR antibody|PAR 1 antibody|PAR-1 antibody|PAR1 antibody|PAR1_HUMAN antibody|Protease activated receptor 1 antibody|Proteinase activated receptor 1 antibody|Proteinase-activated receptor 1 antibody|Thrombin receptor antibody|TR antibody

基因ID

2149

UniProt

P25116

途径

Nuclear Receptor Transcription Pathway, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus