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PAR1 抗体 (AA 267-316)

F2R 适用: 人, 大鼠, 小鼠, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6746560
发货至: 中国
  • 抗原 See all PAR1 (F2R) 抗体
    PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))
    抗原表位
    • 16
    • 15
    • 8
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 267-316
    适用
    • 68
    • 24
    • 22
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 大鼠, 小鼠, Pig, 兔
    宿主
    • 61
    • 7
    • 2
    克隆类型
    • 64
    • 6
    多克隆
    标记
    • 39
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PAR1 antibody is un-conjugated
    应用范围
    • 60
    • 36
    • 13
    • 13
    • 11
    • 8
    • 8
    • 6
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    特异性
    Human F2R / Thrombin Receptor
    预测反应
    Percent identity by BLAST analysis: Mouse, Rat (100%) Dog (92%) Pig (85%) Rabbit (84%).
    纯化方法
    Immunoaffinity purified
    免疫原
    Synthetic peptide located between aa267-316 of human F2R (P25116, NP_001983). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Mouse, Rat (100%), Gibbon, Baboon, Monkey, Galago, Marmoset, Hamster, Dog, Horse (92%), Pig (85%), Rabbit (84%).

    Type of Immunogen: Synthetic peptide
  • 应用备注
    Approved: WB (0.2 - 1 μg/mL)

    Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Distilled water
    浓度
    Lot specific
    缓冲液
    Lyophilized from PBS with 2 % sucrose
    注意事项
    Avoid repeat freeze-thaw cycles.
    储存条件
    4 °C,-20 °C
    储存方法
    Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
    Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
  • Gradin, Larsson, Marklund, Gullberg: "Regulation of microtubule dynamics by extracellular signals: cAMP-dependent protein kinase switches off the activity of oncoprotein 18 in intact cells." in: The Journal of cell biology, Vol. 140, Issue 1, pp. 131-41, (1998) (PubMed).

    Horwitz, Shen, He, Dittmar, Neef, Chen, Schubart: "The microtubule-destabilizing activity of metablastin (p19) is controlled by phosphorylation." in: The Journal of biological chemistry, Vol. 272, Issue 13, pp. 8129-32, (1997) (PubMed).

    Larsson, Marklund, Gradin, Brattsand, Gullberg: "Control of microtubule dynamics by oncoprotein 18: dissection of the regulatory role of multisite phosphorylation during mitosis." in: Molecular and cellular biology, Vol. 17, Issue 9, pp. 5530-9, (1997) (PubMed).

  • 抗原
    PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))
    别名
    F2R / Thrombin Receptor / PAR1 (F2R 产品)
    别名
    CF2R antibody, HTR antibody, PAR-1 antibody, PAR1 antibody, TR antibody, Par1 antibody, TRGPC antibody, AI482343 antibody, Cf2r antibody, ThrR antibody, Par-1 antibody, f2r-a antibody, par1 antibody, coagulation factor II thrombin receptor antibody, coagulation factor II (thrombin) receptor antibody, coagulation factor 2 (thrombin) receptor L homeolog antibody, F2R antibody, F2r antibody, f2r.L antibody
    背景
    Name/Gene ID: F2R
    Subfamily: Proteinase-activated
    Family: GPCR

    Synonyms: F2R, CF2R, Coagulation factor II receptor, PAR1, PAR-1, Thrombin receptor, TR, HTR, Protease-activated receptor 1
    基因ID
    2149
    NCBI登录号
    NP_001983
    UniProt
    P25116
    途径
    Nuclear Receptor Transcription Pathway, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus
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