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Midkine 抗体 (AA 21-143)

MDK 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042356
发货至: 中国
  • 抗原 See all Midkine (MDK) 抗体
    Midkine (MDK) (Midkine (Neurite Growth-Promoting Factor 2) (MDK))
    抗原表位
    • 8
    • 8
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 21-143
    适用
    • 72
    • 30
    • 26
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 70
    • 13
    克隆类型
    • 64
    • 19
    多克隆
    标记
    • 37
    • 18
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Midkine antibody is un-conjugated
    应用范围
    • 52
    • 26
    • 23
    • 13
    • 10
    • 7
    • 7
    • 6
    • 5
    • 3
    • 1
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Midkine(MDK) detection. Tested with WB in Human.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Midkine(MDK) detection. Tested with WB in Human.
    Gene Name: midkine (neurite growth-promoting factor 2)
    Protein Name: Midkine
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human Midkine recombinant protein (Position: V21-D143). Human Midkine shares 87% and 89% amino acid (aa) sequence identity with mouse and rat Midkine, respectively.
    亚型
    IgG
    Top Product
    Discover our top product MDK Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for Midkine is approximately 0.25 ng/lane under reducing conditions.
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    Midkine (MDK) (Midkine (Neurite Growth-Promoting Factor 2) (MDK))
    别名
    MDK (MDK 产品)
    别名
    ARAP antibody, MK antibody, NEGF2 antibody, Mek antibody, MK-B antibody, PTF-alpha-1 antibody, mdk antibody, midkine antibody, negf2 antibody, RIHB antibody, cb518 antibody, fb79b05 antibody, fj33b02 antibody, fj48a12 antibody, mdk2 antibody, plei2 antibody, wu:fb79b05 antibody, wu:fj33b02 antibody, wu:fj48a12 antibody, MK-A antibody, PTF-alpha-2 antibody, X-PTF-alpha1 antibody, XMK antibody, mdk-a antibody, mdk-b antibody, midkine antibody, midkine L homeolog antibody, midkine (neurite growth-promoting factor 2) antibody, midkine b antibody, midkine S homeolog antibody, MDK antibody, Mdk antibody, mdk.L antibody, mdkb antibody, mdk.S antibody
    背景
    Midkine(MK or MDK), also known as neurite growth-promoting factor 2(NEGF2), is a protein that in humans is encoded by the MDK gene. Midkine is a basic heparin-binding growth factor of low molecular weight, and forms a family with pleiotrophin(NEGF1, 46 % homologous with MK). It is a nonglycosylated protein, composed of two domains held by disulfide bridges. It is a developmentally important retinoic acid-responsive gene product strongly induced during mid-gestation, hence the name midkine. Restricted mainly to certain tissues in the normal adult, it is strongly induced during oncogenesis, inflammation and tissue repair. Midkine is pleiotropic, capable of exerting activities such as cell proliferation, cell migration, angiogenesis and fibrinolysis. A molecular complex containing receptor-type tyrosine phosphatase zeta(PTPζ), low density lipoprotein receptor-related protein(LRP1), anaplastic leukemia kinase (ALK) and syndecans is considered to be its receptor.

    Synonyms: Amphiregulin associated protein antibody|Amphiregulin-associated protein antibody|ARAP antibody|FLJ27379 antibody|MDK antibody|Midgestation and kidney protein antibody|Midkine antibody|MK 1 antibody|MK antibody|MK_HUMAN antibody|MK1 antibody|NEGF 2 antibody|NEGF2 antibody|neurite growth promoting factor 2 antibody|Neurite outgrowth promoting protein antibody|Neurite outgrowth-promoting factor 2 antibody|Neurite outgrowth-promoting protein antibody|Retinoic acid inducible factor antibody
    基因ID
    4192
    UniProt
    P21741
    途径
    RTK signaling, M Phase, Skeletal Muscle Fiber Development
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