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DIO2 抗体 (AA 217-228)

DIO2 适用: 人, 小鼠, Pig ELISA, IHC, IHC (pfa) 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN303850
发货至: 中国
  • 抗原 See all DIO2 抗体
    DIO2 (Deiodinase, Iodothyronine, Type II (DIO2))
    抗原表位
    • 15
    • 9
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 217-228
    适用
    人, 小鼠, Pig
    宿主
    • 43
    • 1
    • 1
    山羊
    克隆类型
    • 44
    • 1
    多克隆
    标记
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DIO2 antibody is un-conjugated
    应用范围
    • 32
    • 18
    • 13
    • 13
    • 8
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraformaldehyde) (IHC (pfa))
    特异性
    Human DIO2. This antibody is expected to recognise both reported isoform a (NP_000784.2 and NP_054644.1) and isoform b (NP_001007024.1).
    预测反应
    Percent identity by BLAST analysis: Human, Gorilla, Pig (100%) Mouse, Rat, Sheep, Goat, Panda, Bovine, Rabbit, Chicken, Frog (92%) Hamster, Xenopus (83%).
    纯化方法
    Immunoaffinity purified
    免疫原
    Synthetic peptide EVKKHQNQEDRC from an internal region of human DIO2 (NP_000784.2, NP_054644.1, NP_001007024.1). Percent identity by BLAST analysis: Human, Gorilla, Pig (100%), Mouse, Rat, Sheep, Goat, Panda, Bovine, Rabbit, Chicken, Frog (92%), Hamster, Xenopus (83%).

    Type of Immunogen: Synthetic peptide
    Top Product
    Discover our top product DIO2 Primary Antibody
  • 应用备注
    Approved: IHC, IHC-Pfa, Peptide-ELISA (1:128000)

    Usage: IHC: Cryo-sectioned (4 % PFA-fixed) Mouse Brain (Hippocampus) shows staining in the granular layer of the dentate gyrus. Recommended concentration, 2-3 μg/mL. Data obtained from anonymous customer. Western blot: Preliminary experiments gave an approx 65-70 kDa band in Human Heart and Thyroid lysates after 0.05 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 30.5 kDa according to NP_NP_000784.2 and of 34.6 kDa according to NP_001007024.1. The 65-70 kDa band was successfully blocked by incubation with the immunizing peptide.
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Minimize freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze-thaw cycles.
  • 抗原
    DIO2 (Deiodinase, Iodothyronine, Type II (DIO2))
    别名
    DIO2 (DIO2 产品)
    别名
    5DII antibody, D2 antibody, DIOII antibody, SelY antibody, TXDI2 antibody, AI324267 antibody, Deio2 antibody, cb684 antibody, DIO2 antibody, dio2-A antibody, 5dii antibody, sely antibody, txdi2 antibody, iodothyronine deiodinase 2 antibody, deiodinase, iodothyronine, type II antibody, deiodinase, iodothyronine, type 2 L homeolog antibody, deiodinase, iodothyronine, type 2 antibody, type II iodothyronine deiodinase antibody, DIO2 antibody, Dio2 antibody, dio2 antibody, dio2.L antibody, LOC100861220 antibody
    背景
    Name/Gene ID: DIO2

    Synonyms: DIO2, 5DII, D2, DIOII, ITDI2, Type 2 DI, TXDI2, Type-II 5-deiodinase, SelY, Type-II 5deiodinase, Thyroxine deiodinase, type II
    基因ID
    1734
    NCBI登录号
    NP_000784, NP_054644, NP_001007024
    UniProt
    Q92813
    途径
    Hormone Transport, Hormone Activity
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