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PIAS4 抗体 (C-Term)

PIAS4 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3032370
发货至: 中国
  • 抗原 See all PIAS4 抗体
    PIAS4 (Protein Inhibitor of Activated STAT, 4 (PIAS4))
    抗原表位
    • 14
    • 8
    • 8
    • 8
    • 7
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 55
    • 33
    • 9
    • 4
    • 3
    • 3
    • 3
    • 3
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    • 2
    • 2
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    • 1
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    人, 小鼠, 大鼠
    宿主
    • 59
    • 2
    克隆类型
    • 60
    • 1
    多克隆
    标记
    • 31
    • 6
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
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    This PIAS4 antibody is un-conjugated
    应用范围
    • 50
    • 34
    • 20
    • 9
    • 4
    • 3
    • 3
    Western Blotting (WB)
    纯化方法
    Antigen affinity
    免疫原
    An amino acid sequence from the C-terminus of human E3 SUMO-protein ligase PIASg (HPELCKALVKEKLRLD) was used as the immunogen for this PIASg antibody (100% homologous in human, mouse and rat).
    亚型
    IgG
    Top Product
    Discover our top product PIAS4 Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the PIASg antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the PIASg antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    PIAS4 (Protein Inhibitor of Activated STAT, 4 (PIAS4))
    别名
    PIASg (PIAS4) (PIAS4 产品)
    别名
    PIASY antibody, Piasg antibody, ZMIZ6 antibody, pias4 antibody, piasy antibody, wu:fc54c11 antibody, wu:fi18c10 antibody, wu:fi20e09 antibody, wu:fk93f11 antibody, zgc:66410 antibody, piasg antibody, zmiz6 antibody, LOC100219439 antibody, Pias-gamma antibody, pias4l antibody, wu:fi26h11 antibody, zgc:63923 antibody, protein inhibitor of activated STAT 4 antibody, protein inhibitor of activated STAT, 4 antibody, protein inhibitor of activated STAT, 4a antibody, protein inhibitor of activated STAT 4 L homeolog antibody, protein inhibitor of activated STAT, 4b antibody, PIAS4 antibody, Pias4 antibody, pias4a antibody, pias4.L antibody, pias4 antibody, pias4b antibody
    背景
    Protein inhibitor of activated STAT protein 4 (PIAS4) or Protein inhibitor of activated STAT protein gamma (PIASg or PIASy) is an enzyme that in humans is encoded by the PIAS4 gene. This gene is mapped to 19p13.3. This gene plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53/TP53 pathway, the Wnt pathway and the steroid hormone signaling pathway. PIASg functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. This gene involved in gene silencing.
    UniProt
    Q8N2W9
    途径
    JAK/STAT Signaling, Interferon-gamma Pathway, Positive Regulation of Response to DNA Damage Stimulus
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