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PIAS4 抗体 (AA 66-241)

PIAS4 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7150970
发货至: 中国
  • 抗原 See all PIAS4 抗体
    PIAS4 (Protein Inhibitor of Activated STAT, 4 (PIAS4))
    抗原表位
    • 14
    • 8
    • 8
    • 8
    • 7
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 66-241
    适用
    • 55
    • 33
    • 9
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 59
    • 2
    克隆类型
    • 60
    • 1
    多克隆
    标记
    • 31
    • 6
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PIAS4 antibody is un-conjugated
    应用范围
    • 51
    • 33
    • 19
    • 9
    • 5
    • 4
    • 3
    ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human E3 SUMO-protein ligase PIAS4 protein (66-241AA)
    亚型
    IgG
    Top Product
    Discover our top product PIAS4 Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:500-1:1000,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    PIAS4 (Protein Inhibitor of Activated STAT, 4 (PIAS4))
    别名
    PIAS4 (PIAS4 产品)
    别名
    PIASY antibody, Piasg antibody, ZMIZ6 antibody, pias4 antibody, piasy antibody, wu:fc54c11 antibody, wu:fi18c10 antibody, wu:fi20e09 antibody, wu:fk93f11 antibody, zgc:66410 antibody, piasg antibody, zmiz6 antibody, LOC100219439 antibody, Pias-gamma antibody, pias4l antibody, wu:fi26h11 antibody, zgc:63923 antibody, protein inhibitor of activated STAT 4 antibody, protein inhibitor of activated STAT, 4 antibody, protein inhibitor of activated STAT, 4a antibody, protein inhibitor of activated STAT 4 L homeolog antibody, protein inhibitor of activated STAT, 4b antibody, PIAS4 antibody, Pias4 antibody, pias4a antibody, pias4.L antibody, pias4 antibody, pias4b antibody
    背景

    Background: Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53/TP53 pathway, the Wnt pathway and the steroid hormone signaling pathway. Involved in gene silencing. Mediates sumoylation of CEBPA, PARK7, HERC2, MYB, TCF4 and RNF168. In Wnt signaling, represses LEF1 and enhances TCF4 transcriptional activities through promoting their sumoylations. Enhances the sumoylation of MTA1 and may participate in its paralog-selective sumoylation.

    Aliases: E3 SUMO protein ligase PIAS4 antibody, E3 SUMO-protein ligase PIAS4 antibody, FLJ12419 antibody, MGC35296 antibody, PAIASgamma antibody, PIAS 4 antibody, PIAS gamma antibody, PIAS-gamma antibody, Pias4 antibody, PIAS4_HUMAN antibody, PIASG antibody, PIASgamma antibody, PIASy antibody, Protein inhibitor of activated STAT 4 antibody, Protein inhibitor of activated STAT protein 4 antibody, Protein inhibitor of activated STAT protein gamma antibody, Protein inhibitor of activated STAT protein PIASy antibody, Zinc finger MIZ type containing 6 antibody, ZMIZ 6 antibody, ZMIZ6 antibody

    UniProt
    Q8N2W9
    途径
    JAK/STAT Signaling, Interferon-gamma Pathway, Positive Regulation of Response to DNA Damage Stimulus
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