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PD-1 抗体 (C-Term)

PDCD1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN303234
发货至: 中国
  • 抗原 See all PD-1 (PDCD1) 抗体
    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
    抗原表位
    • 16
    • 8
    • 5
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    C-Term
    适用
    • 127
    • 71
    • 25
    • 5
    • 3
    • 1
    人, 小鼠
    宿主
    • 72
    • 58
    • 23
    • 11
    • 9
    • 3
    • 1
    克隆类型
    • 118
    • 56
    • 2
    多克隆
    标记
    • 86
    • 13
    • 10
    • 10
    • 5
    • 5
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    This PD-1 antibody is un-conjugated
    应用范围
    • 114
    • 55
    • 42
    • 36
    • 32
    • 17
    • 13
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    • 13
    • 10
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    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody is specific to CD279/PDCD1
    交叉反应 (详细)
    Species reactivity (expected):Mouse.
    Species reactivity (tested):Human.
    纯化方法
    Immunoaffinity Chromatography
    免疫原
    Synthetic peptide corresponding to 16 Amino Acid from near the carboxy terminus of Human PDCD1.
    Top Product
    Discover our top product PDCD1 Primary Antibody
  • 应用备注
    Western Blot. Immunohistochemistry on Paraffin Sections: 2.5 μg/mL. This antibody was validated for use in immunohistochemistry on a panel of 21formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigenretrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides wereincubated with biotinylated secondary antibody, followed by alkalinephosphatase-streptavidin and chromogen.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
    别名
    CD279 / PD1 (PDCD1 产品)
    别名
    CD279 antibody, PD-1 antibody, PD1 antibody, SLEB2 antibody, hPD-1 antibody, hPD-l antibody, Ly101 antibody, Pdc1 antibody, programmed cell death 1 antibody, PDCD1 antibody, Pdcd1 antibody
    背景
    This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.Synonyms: PDCD1, Programmed cell death protein 1, Protein PD-1, hPD-1
    基因ID
    5133
    NCBI登录号
    NP_005009
    UniProt
    Q15116
    途径
    Cancer Immune Checkpoints
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