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PGK1 抗体 (Middle Region)

PGK1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3032222
发货至: 中国
  • 抗原 See all PGK1 抗体
    PGK1 (Phosphoglycerate Kinase 1 (PGK1))
    抗原表位
    • 8
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    Middle Region
    适用
    • 71
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    • 5
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    • 4
    • 4
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    人, 小鼠, 大鼠
    宿主
    • 64
    • 9
    • 1
    • 1
    克隆类型
    • 55
    • 17
    多克隆
    标记
    • 49
    • 5
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    • 2
    • 2
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    • 2
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    This PGK1 antibody is un-conjugated
    应用范围
    • 56
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    • 7
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    • 2
    • 2
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    • 1
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    Western Blotting (WB)
    纯化方法
    Antigen affinity
    免疫原
    An amino acid sequence from the middle region of human Phosphoglycerate Kinase 1 (FGTAHRAHSSMVGVN) was used as the immunogen for this PGK1 antibody (100% homologous in human, mouse and rat).
    亚型
    IgG
    Top Product
    Discover our top product PGK1 Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the PGK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL, IHC-P: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the PGK1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    PGK1 (Phosphoglycerate Kinase 1 (PGK1))
    别名
    PGK1 (PGK1 产品)
    别名
    MIG10 antibody, PGKA antibody, Pgk-1 antibody, Pgk antibody, PGK antibody, wu:fd59b07 antibody, wu:fj36g06 antibody, zgc:56252 antibody, zgc:77899 antibody, PGK1 antibody, phosphoglycerate kinase 1 antibody, pgk2 antibody, pgka antibody, phosphoglycerate kinase 1 antibody, phosphoglycerate kinase 1 L homeolog antibody, PGK1 antibody, Pgk1 antibody, pgk1 antibody, LOC100348124 antibody, pgk1.L antibody
    背景
    Phosphoglycerate Kinase 1, also known as PGKA, is an enzyme that in humans is encoded by the PGK1 gene. Willard et al.(1985) used a cDNA for human PGK to map the functional PGK1 gene to Xq13. Disulfide bonds in secreted proteins are considered to be inert because of the oxidizing nature of the extracellular milieu. An exception to this rule is a reductase secreted by tumor cells that reduces disulfide bonds in the serine proteinase plasmin. Lay et al.(2000) showed that the plasmin reductase isolated from conditioned medium of fibrosarcoma cells is the glycolytic enzyme phosphoglycerate kinase. Recombinant phosphoglycerate kinase had the same specific activity as the fibrosarcoma-derived protein. Plasma of mice bearing fibrosarcoma tumors contained several-fold more phosphoglycerate kinase, as compared with mice without tumors.
    UniProt
    P00558
    途径
    Cellular Glucan Metabolic Process
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