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- 抗原 See all NR1H3 抗体
- NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NR1H3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Antigen affinity
- 免疫原
- An amino acid sequence from the C-terminus of human LXR alpha (NVQDQLQVERLQHTY) was used as the immunogen for this LXR alpha antibody (100% homologous in human, mouse and rat).
- 亚型
- IgG
- Top Product
- Discover our top product NR1H3 Primary Antibody
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anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) antibody
NR1H3 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (C-Term) antibodyNR1H3 适用: 人, 小鼠, 大鼠, Cow, 非洲爪蟾, 犬, 山羊, 马, 兔, Pig, 豚鼠, 猴, 斑马鱼, 小鸡, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (AA 1-387) antibodyNR1H3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E9 unconjugated
anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (AA 50-330) antibodyNR1H3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (AA 1-402) antibodyNR1H3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (AA 1-402) antibodyNR1H3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (C-Term) antibodyNR1H3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (AA 50-150) antibodyNR1H3 适用: 人, 小鼠, 大鼠, 猴, 小鸡, 灵长类 WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (N-Term) antibodyNR1H3 适用: 人, 小鼠 WB, ChIP-seq, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (AA 361-447) antibodyNR1H3 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- The stated application concentrations are suggested starting amounts. Titration of the LXR alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
- 限制
- 仅限研究用
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- 缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- 储存条件
- -20 °C
- 储存方法
- After reconstitution, the LXR alpha antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- 抗原
- NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
- 别名
- LXR alpha (NR1H3) (NR1H3 产品)
- 别名
- NR1H3 antibody, LXR-a antibody, LXRA antibody, RLD-1 antibody, AU018371 antibody, LXR antibody, RLD1 antibody, Unr1 antibody, LXRalpha antibody, LXR-alpha antibody, im:7141239 antibody, wu:fd59b01 antibody, zgc:113339 antibody, zgc:158542 antibody, nuclear receptor subfamily 1 group H member 3 antibody, nuclear receptor subfamily 1, group H, member 3 antibody, NR1H3 antibody, nr1h3 antibody, Nr1h3 antibody
- 背景
- Liver X receptor alpha, also called NR1H3, is a tissue-specific cofactor that permits RXRA to function as a potent 9cRA receptor with a distinct target gene specificity. It specifically interacts with RXRA in vivo to form a functional heterodimer in which RXRA is the ligand-binding subunit. Additionally, Liver X receptor activity is critical for physiologic lipid metabolism and transport. They are endogenous inhibitors of atherogenesis and are targets for therapeutic intervention in cardiovascular disease. Furthermore, they and their ligands are negative regulators of macrophage inflammatory gene expression. Liver X receptors act as a transcriptional switch that integrates hepatic glucose metabolism and fatty acid synthesis. The LXR-IDOL-LDLR axis defines a complementary pathway to sterol response element-binding proteins for sterol regulation of cholesterol uptake.
- UniProt
- Q13133
- 途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding, Cellular Response to Molecule of Bacterial Origin, Hepatitis C
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