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NOTCH4 抗体 (C-Term)

NOTCH4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3032034
发货至: 中国
  • 抗原 See all NOTCH4 抗体
    NOTCH4 (Notch 4 (NOTCH4))
    抗原表位
    • 15
    • 9
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 39
    • 29
    • 20
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    宿主
    • 53
    • 3
    • 2
    克隆类型
    • 49
    • 9
    多克隆
    标记
    • 30
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NOTCH4 antibody is un-conjugated
    应用范围
    • 27
    • 17
    • 13
    • 13
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    Western Blotting (WB)
    纯化方法
    Antigen affinity
    免疫原
    An amino acid sequence from the C-terminus of human NOTCH4 (DVAHQRNHWDLLTL) was used as the immunogen for this NOTCH4 antibody.
    亚型
    IgG
    Top Product
    Discover our top product NOTCH4 Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the NOTCH4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the NOTCH4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    NOTCH4 (Notch 4 (NOTCH4))
    别名
    NOTCH4 (NOTCH4 产品)
    别名
    INT3 antibody, NOTCH3 antibody, Int-3 antibody, Int3 antibody, N4 antibody, Notch4 antibody, notch 4 antibody, neurogenic locus notch homolog protein 4 antibody, NOTCH4 antibody, Notch4 antibody, LOC100712850 antibody
    背景
    NOTCH4 is a member of the Notch family. In situ hybridization revealed that Notch4 transcripts are primarily restricted to endothelial cells in embryonic and adult life, suggesting a specific role for the protein during development of vertebrate endothelium. The sequences of the mouse and human proteins are 82 % identical. Northern blot analysis revealed that NOTCH4(S) is the major transcript and is expressed in a wide variety of tissues. Fluorescence in situ hybridization confirmed the location of the gene at chromosome 6p21.3. In linkage disequilibrium mapping of the MHC region in 80 British parent-offspring trios, Wei and Hemmings(2000) found that NOTCH4 was highly associated with schizophrenia. Repression of Notch4 resolved ataxia and reversed the disease progression, demonstrating that it is not only sufficient to induce but also required to sustain the disease.
    UniProt
    Q99466
    途径
    Notch Signaling
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