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Lamin A/C 抗体 (AA 455-469)

Name: Lamin A/C 抗体 (AA 455-469)
SKU: ABIN3031585
Availability: OutOfStock

This anti-Lamin A/C antibody is a 兔多克隆 antibody detecting Lamin A/C in WB, ICC 和 IHC (p). Suitable for 人, 小鼠和大鼠.

Western blot testing of Lamin A/C antibody and Lane 1: HeLa; 2: A431 cell lysate (Lamin A/C 抗体 (AA 455-469))

IHC-P: Lamin A/C antibody testing of human lung cancer tissue (Lamin A/C 抗体 (AA 455-469))

IHC

IHC-P: Lamin A/C antibody testing of mouse intestine tissue (Lamin A/C 抗体 (AA 455-469))

IHC

Western blot testing of Lamin A/C antibody and Lane 1: HeLa (Lamin A/C 抗体 (AA 455-469))

IHC

IHC-P: Lamin A/C antibody testing of rat intestine tissue (Lamin A/C 抗体 (AA 455-469))

IHC

6 images

产品编号 ABIN3031585

发货至: 中国

Quick Overview for Lamin A/C 抗体 (AA 455-469) (ABIN3031585)

抗原

See all Lamin A/C (LMNA) 抗体

Lamin A/C (LMNA)

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This Lamin A/C antibody is un-conjugated

应用范围

Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Discover our top product LMNA Primary Antibody

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AA 455-469

纯化方法

Antigen affinity

免疫原

Amino acids 455-469 (RNKSNEDQSMGNWQI) were used as the immunogen for this Lamin A/C antibody (100% homologous in human, mouse and rat).

亚型

IgG
anti-Lamin A/C (LMNA) (AA 403-572) antibody
LMNA 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Lamin A/C (LMNA) antibody
KO Validated LMNA 适用: 人 WB, IF, IP, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Lamin A/C (LMNA) (pSer392) antibody
LMNA 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Lamin A/C (LMNA) antibody
KO Validated LMNA 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated

anti-Lamin A/C (LMNA) antibody
LMNA 适用: 人 IHC, ELISA, IF, IP, FACS 宿主: 兔 Monoclonal 4H7 unconjugated Recombinant Antibody

anti-Lamin A/C (LMNA) antibody
LMNA 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 4E7 unconjugated

anti-Lamin A/C (LMNA) (AA 481-646) antibody
LMNA 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Lamin A/C (LMNA) antibody
LMNA 适用: 人, 小鼠, 大鼠, Cow, 犬 WB, IHC, ICC, FACS, IHC (fro) 宿主: 小鼠 Monoclonal 133A2 unconjugated

anti-Lamin A/C (LMNA) (C-Term) antibody
LMNA 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 猴, 兔, 马, Hamster, 小鸡, 绵羊, 豚鼠, Avian, Cat, 驴, 山羊 WB 宿主: 山羊 Polyclonal unconjugated

anti-Lamin A/C (LMNA) (AA 1-664) antibody
LMNA 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

应用备注

The stated application concentrations are suggested starting points. Titration of the Lamin A/C antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL

限制

仅限研究用
缓冲液

0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

储存条件

-20 °C

储存方法

After reconstitution, the Lamin A/C antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
抗原

Lamin A/C (LMNA)

别名

Lamin A/C

背景

Lamins are structural protein components of the nuclear lamina, a protein network underlying the inner nuclear membrane that determines nuclear shape and size. There are three types of lamins, A, B and C. The Lamin A/C (LMNA) gene contains 12 exons. Alternative splicing within exon 10 gives rise to two different mRNAs that code for pre-lamin A and C. Lamin A/C mapped to 1q21.2-q21.3 and mutations in this gene cause a variety of human diseases including Emery-Dreifuss muscular dystrophy, dilated cardiomyopathy, and Hutchinson-Gilford progeria syndrome. Protein deficiency is thus associated with both defective nuclear mechanics and impaired mechanically activated gene transcription.

UniProt

P02545

途径

Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus