IL-6 抗体 (AA 195-212)
Quick Overview for IL-6 抗体 (AA 195-212) (ABIN3031291)
抗原
See all IL-6 (IL6) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 195-212
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纯化方法
- Antigen affinity
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免疫原
- Amino acids 195-212 (LRSFKEFLQSSLRALRQM) were used as the immunogen for this IL-6 antibody.
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亚型
- IgG
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应用备注
- The stated application concentrations are suggested starting points. Titration of the IL-6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the IL-6 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- IL-6 (IL6) (Interleukin 6 (IL6))
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别名
- IL-6
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背景
- Interleukin-6 is a protein that in humans is encoded by the IL-6 gene. It is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. It is secreted by T cells and macrophages to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation. Interleukin-6 is one of the most important mediators of fever and of the acute phase response. It is also essential for hybridoma growth and is found in many supplemental cloning media such as briclone. Bowcock et al.(1988) assigned the IL-6 gene to chromosome 7p21. By in situ hybridization and Southern blot analysis of mouse-human hybrid cell lines, Sutherland et al.(1988) mapped the IL6 gene to chromosome 7p15.
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UniProt
- P05231
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途径
- TLR signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
抗原
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