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- 抗原 See all FOXP1 抗体
- FOXP1 (Forkhead Box P1 (FOXP1))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FOXP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- Antigen affinity
- 免疫原
- An amino acid sequence from the C-terminus of human FOXP1 (HSPDFDHDRDYEDEPVNEDME) was used as the immunogen for this FOXP1 antibody (100% homologous in human, mouse and rat).
- 亚型
- IgG
- Top Product
- Discover our top product FOXP1 Primary Antibody
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anti-Forkhead Box P1 (FOXP1) (AA 481-677) antibody
FOXP1 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 6-00E-04 unconjugated
anti-Forkhead Box P1 (FOXP1) (C-Term) antibodyFOXP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box P1 (FOXP1) (AA 650-677) antibodyFOXP1 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box P1 (FOXP1) (C-Term) antibodyFOXP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box P1 (FOXP1) (AA 541-677) antibodyFOXP1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box P1 (FOXP1) (AA 1-114) antibodyFOXP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E3-G11 unconjugated
anti-Forkhead Box P1 (FOXP1) (AA 223-270) antibodyFOXP1 适用: 人, 小鼠, 大鼠, 兔, 犬, 马, 猴, 豚鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box P1 (FOXP1) (AA 650-677), (C-Term) antibodyFOXP1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB24604 unconjugated
anti-Forkhead Box P1 (FOXP1) (N-Term) antibodyFOXP1 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box P1 (FOXP1) (AA 581-705) antibodyFOXP1 适用: 小鼠, 兔 ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- The stated application concentrations are suggested starting amounts. Titration of the FOXP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
- 限制
- 仅限研究用
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- 缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- 储存条件
- -20 °C
- 储存方法
- After reconstitution, the FOXP1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- 抗原
- FOXP1 (Forkhead Box P1 (FOXP1))
- 别名
- FOXP1 (FOXP1 产品)
- 别名
- 12CC4 antibody, QRF1 antibody, hFKH1B antibody, 3110052D19Rik antibody, 4932443N09Rik antibody, AI461938 antibody, AW494214 antibody, foxp1 antibody, im:7139058 antibody, wu:fc83a06 antibody, FOXP1 antibody, MGC145686 antibody, 12cc4 antibody, fkh1b antibody, hspc215 antibody, qrf1 antibody, xlfoxp1 antibody, im:7146611 antibody, wu:fb97f01 antibody, zgc:154010 antibody, forkhead box P1 antibody, forkhead box P1b antibody, forkhead box P1 S homeolog antibody, forkhead box P1a antibody, FOXP1 antibody, Foxp1 antibody, foxp1b antibody, foxp1 antibody, foxp1.S antibody, foxp1a antibody
- 背景
- Forkhead box P1 is a gene that is necessary for the proper development of the brain and lung in mammals. It is a member of the large FOX family of transcription factors. This gene belongs to subfamily P of the forkhead box(FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region(3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms. It was shown that the embryonic stem cell(ESC)-specific isoform of FOXP1 stimulates the expression of transcription factor genes required for pluripotency, including OCT4, NANOG, NR5A2, and GDF3, while concomitantly repressing genes required for ESC differentiation. This isoform also promotes the maintenance of ESC pluripotency and contributes to efficient reprogramming of somatic cells into induced pluripotent stem cells. These results reveal a pivotal role for an Alternative splicing event in the regulation of pluripotency through the control of critical ESC-specific transcriptional programs(2).
- UniProt
- Q9H334
- 途径
- Chromatin Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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