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FOXP1 抗体 (AA 541-677)

FOXP1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7153092
发货至: 中国
  • 抗原 See all FOXP1 抗体
    FOXP1 (Forkhead Box P1 (FOXP1))
    抗原表位
    • 16
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    • 1
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    AA 541-677
    适用
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    宿主
    • 83
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    克隆类型
    • 72
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    • 1
    多克隆
    标记
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    This FOXP1 antibody is un-conjugated
    应用范围
    • 49
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Forkhead box protein P1 protein (541-677AA)
    亚型
    IgG
    Top Product
    Discover our top product FOXP1 Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    FOXP1 (Forkhead Box P1 (FOXP1))
    别名
    FOXP1 (FOXP1 产品)
    别名
    12CC4 antibody, QRF1 antibody, hFKH1B antibody, 3110052D19Rik antibody, 4932443N09Rik antibody, AI461938 antibody, AW494214 antibody, foxp1 antibody, im:7139058 antibody, wu:fc83a06 antibody, FOXP1 antibody, MGC145686 antibody, 12cc4 antibody, fkh1b antibody, hspc215 antibody, qrf1 antibody, xlfoxp1 antibody, im:7146611 antibody, wu:fb97f01 antibody, zgc:154010 antibody, forkhead box P1 antibody, forkhead box P1b antibody, forkhead box P1 S homeolog antibody, forkhead box P1a antibody, FOXP1 antibody, Foxp1 antibody, foxp1b antibody, foxp1 antibody, foxp1.S antibody, foxp1a antibody
    背景

    Background: Transcriptional repressor (PubMed:18347093, PubMed:26647308). Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential (By similarity). Plays an important role in the specification and differentiation of lung epithelium. Acts cooperatively with FOXP4 to regulate lung secretory epithelial cell fate and regeneration by restricting the goblet cell lineage program, the function may involve regulation of AGR2. Essential transcriptional regulator of B-cell development. Involved in regulation of cardiac muscle cell proliferation. Involved in the columnar organization of spinal motor neurons. Promotes the formation of the lateral motor neuron column (LMC) and the preganglionic motor column (PGC) and is required for respective appropriate motor axon projections. The segment-appropriate generation of spinal chord motor columns requires cooperation with other Hox proteins. Can regulate PITX3 promoter activity, may promote midbrain identity in embryonic stem cell-derived dopamine neurons by regulating PITX3. Negatively regulates the differentiation of T follicular helper cells T(FH)s. Involved in maintainance of hair follicle stem cell quiescence, the function probably involves regulation of FGF18 (By similarity). Represses transcription of various pro-apoptotic genes and cooperates with NF-kappa B-signaling in promoting B-cell expansion by inhibition of caspase-dependent apoptosis (PubMed:25267198). Binds to CSF1R promoter elements and is involved in regulation of monocyte differentiation and macrophage functions, repression of CSF1R in monocytes seems to involve NCOR2 as corepressor (PubMed:15286807, PubMed:18799727, PubMed:18347093). Involved in endothelial cell proliferation, tube formation and migration indicative for a role in angiogenesis, the role in neovascularization seems to implicate suppression of SEMA5B (PubMed:24023716). Can negatively regulate androgen receptor signaling (PubMed:18640093).

    Aliases: 12CC4 antibody, FLJ23741 antibody, Fork head related protein like B antibody, Forkhead box P1 antibody, Forkhead box protein P1 antibody, FOX P1 antibody, FOXP 1 antibody, foxp1 antibody, FOXP1_HUMAN antibody, Glutamine rich factor 1 antibody, hFKH1B antibody, HSPC215 antibody, MGC12942 antibody, MGC88572 antibody, MGC99551 antibody, QRF 1 antibody, QRF1 antibody

    UniProt
    Q9H334
    途径
    Chromatin Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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