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RAD51 抗体 (AA 1-258)

This anti-RAD51 antibody is a 兔 多克隆 antibody detecting RAD51 in WB 和 IHC (p). Suitable for 人 和 大鼠.
产品编号 ABIN3030760
发货至: 中国

Quick Overview for RAD51 抗体 (AA 1-258) (ABIN3030760)

抗原

See all RAD51 抗体
RAD51 (DNA Repair Protein Homolog 1 (RAD51))

适用

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人, 大鼠

宿主

  • 107
  • 50
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克隆类型

  • 98
  • 60
多克隆

标记

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This RAD51 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 1-258

    纯化方法

    Antigen affinity

    免疫原

    Human partial recombinant protein (AA 1-258) was used as the immunogen for this Rad51 antibody.

    亚型

    IgG
  • 应用备注

    The stated application concentrations are suggested starting amounts. Titration of the Rad51 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the Rad51 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    RAD51 (DNA Repair Protein Homolog 1 (RAD51))

    别名

    Rad51

    背景

    DNA repair protein RAD51 homolog 1, also known as RAD51A, is a human gene. The Rad51 gene, HsRAD51, is a homolog of RecA of Escherichia coli and functions in recombination and DNA repair. BRCA1 and BRCA2 proteins form a complex with Rad51, and these genes are thought to participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. It is found to interact with < a href=../search_result.php?search_txt=brca>BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis.

    基因ID

    5888

    途径

    DNA Damage Repair
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