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TdT 抗体 (AA 316-509)

DNTT 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3030715
发货至: 中国
  • 抗原 See all TdT (DNTT) 抗体
    TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))
    抗原表位
    • 16
    • 10
    • 8
    • 8
    • 6
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 316-509
    适用
    • 84
    • 18
    • 16
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    宿主
    • 72
    • 12
    克隆类型
    • 69
    • 15
    多克隆
    标记
    • 39
    • 8
    • 7
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This TdT antibody is un-conjugated
    应用范围
    • 52
    • 44
    • 9
    • 8
    • 8
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Antigen affinity
    免疫原
    Human partial recombinant protein (AA 316-509) was used as the immunogen for this TdT antibody.
    亚型
    IgG
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  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the TdT antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the TdT antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))
    别名
    TdT (DNTT 产品)
    别名
    TdT antibody, TDT antibody, BB160593 antibody, Tdt antibody, dntt-A antibody, dntt antibody, DNA nucleotidylexotransferase antibody, deoxynucleotidyltransferase, terminal antibody, DNA nucleotidylexotransferase L homeolog antibody, terminal deoxynucleotidyl transferase antibody, DNTT antibody, dntt antibody, Dntt antibody, dntt.L antibody, tdt antibody
    背景
    Terminal Deoxynucleotidyl Transferase, also known as Terminal transferase, is a unique DNA polymerase that without template direction catalyzes the addition of deoxyribonucleotides onto the 3-prime-hydroxyl end of DNA primers. Its gene is mapped to the region 10q23-q24. And TdT cDNA contains an open reading frame of 1,530 basepairs corresponding to a protein containing 510 amino acids. TdT may be responsible for inserting nucleotides (N regions) at the V(H)-D and D-J(H) junctions of immunoglobulin genes. The enzyme is present in immature thymocytes, some bone marrow cells, transformed pre-B and pre-T cell lines, and leukemia cells. Additionally, TdT catalyses the addition of nucleotides to the 3' terminus of a DNA molecule. Unlike most DNA polymerases it does not require a template. The preferred substrate of this enzyme is a 3'-overhang, but it can also add nucleotides to blunt or recessed 3' ends. Cobalt is a necessary cofactor.
    基因ID
    1791
    途径
    DNA Damage Repair
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