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CRTC1 抗体 (C-Term)

CRTC1 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3030572
发货至: 中国
  • 抗原 See all CRTC1 抗体
    CRTC1 (CREB Regulated Transcription Coactivator 1 (CRTC1))
    抗原表位
    • 22
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 68
    • 37
    • 25
    • 15
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 56
    • 13
    • 1
    克隆类型
    • 56
    • 14
    多克隆
    标记
    • 33
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This CRTC1 antibody is un-conjugated
    应用范围
    • 53
    • 25
    • 20
    • 13
    • 9
    • 8
    • 7
    • 7
    • 6
    • 6
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Antigen affinity
    免疫原
    An amino acid sequence from the C-terminus of human CRTC1 (EQQMAARQANALSHQL) was used as the immunogen for this CRTC1 antibody.
    亚型
    IgG
    Top Product
    Discover our top product CRTC1 Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the CRTC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the CRTC1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    CRTC1 (CREB Regulated Transcription Coactivator 1 (CRTC1))
    别名
    CRTC1 (CRTC1 产品)
    别名
    MECT1 antibody, TORC-1 antibody, TORC1 antibody, WAMTP1 antibody, AI413414 antibody, Mect1 antibody, R74955 antibody, mKIAA0616 antibody, CRTC1 antibody, crtc1 antibody, fc68c05 antibody, pde4cb antibody, si:ch211-255d18.1 antibody, si:ch211-255d18.8 antibody, wu:fc68c05 antibody, CREB regulated transcription coactivator 1 antibody, CREB regulated transcription coactivator 1b antibody, CRTC1 antibody, Crtc1 antibody, crtc1 antibody, crtc1b antibody
    背景
    CREB-Regulated Transcription Coactivator 1, also known as MECT1, TORC1 or KIAA0616, is a protein that in humans is encoded by the CRTC1 gene. By sequence analysis, Tonon et al.(2003) mapped the gene to chromosome 19p13. Kovacs et al.(2007) found that it was expressed in adult mouse brain and cultured neurons, and that it translocated to the nucleus upon concomitant activation of calcium and cAMP signaling pathways. Mair et al.(2011) demonstrated that CRTC1 is a direct AMPK target, and interacts with the CREB homolog-1(CRH1) transcription factor in vivo. The prolongevity effects of activating AMPK or deactivating calcineurin decrease CRTC1 and CRH1 activity and induce transcriptional responses similar to those of CRH1-null worms.
    UniProt
    Q6UUV9
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