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CRTC1 抗体 (AA 1-200)

CRTC1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7266518
发货至: 中国
  • 抗原 See all CRTC1 抗体
    CRTC1 (CREB Regulated Transcription Coactivator 1 (CRTC1))
    抗原表位
    • 22
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1-200
    适用
    • 67
    • 37
    • 25
    • 15
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 55
    • 13
    • 1
    克隆类型
    • 55
    • 14
    多克隆
    标记
    • 32
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This CRTC1 antibody is un-conjugated
    应用范围
    • 52
    • 25
    • 20
    • 13
    • 9
    • 8
    • 7
    • 7
    • 6
    • 6
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    原理
    CRTC1 Rabbit pAb
    序列
    MATSNNPRKF SEKIALHNQK QAEETAAFEE VMKDLSLTRA ARLQLQKSQY LQLGPSRGQY YGGSLPNVNQ IGSGTMDLPF QTPFQSSGLD TSRTTRHHGL VDRVYRERGR LGSPHRRPLS VDKHGRQADS CPYGTMYLSP PADTSWRRTN SDSALHQSTM TPTQPESFSS GSQDVHQKRV LLLTVPGMEE TTSEADKNLS
    交叉反应
    小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human CRTC1 (NP_056136.2).
    亚型
    IgG
    Top Product
    Discover our top product CRTC1 Primary Antibody
  • 应用备注
    WB,1:200 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    CRTC1 (CREB Regulated Transcription Coactivator 1 (CRTC1))
    别名
    CRTC1 (CRTC1 产品)
    别名
    MECT1 antibody, TORC-1 antibody, TORC1 antibody, WAMTP1 antibody, AI413414 antibody, Mect1 antibody, R74955 antibody, mKIAA0616 antibody, CRTC1 antibody, crtc1 antibody, fc68c05 antibody, pde4cb antibody, si:ch211-255d18.1 antibody, si:ch211-255d18.8 antibody, wu:fc68c05 antibody, CREB regulated transcription coactivator 1 antibody, CREB regulated transcription coactivator 1b antibody, CRTC1 antibody, Crtc1 antibody, crtc1 antibody, crtc1b antibody
    背景
    Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. In the hippocampus, involved in late-phase long-term potentiation (L-LTP maintenance at the Schaffer collateral-CA1 synapses. May be required for dendritic growth of developing cortical neurons (By similarity. In concert with SIK1, regulates the light-induced entrainment of the circadian clock. In response to light stimulus, coactivates the CREB-mediated transcription of PER1 which plays an important role in the photic entrainment of the circadian clock.,CRTC1,MECT1,TORC-1,TORC1,WAMTP1,Epigenetics & Nuclear Signaling,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial Biogenesis,CRTC1
    分子量
    62kDa/67kDa/68kDa
    基因ID
    23373
    UniProt
    Q6UUV9
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