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Caspase 8 抗体 (AA 240-259)

This anti-Caspase 8 antibody is a 兔多克隆 antibody detecting Caspase 8 in WB. Suitable for 人, 小鼠和大鼠.

Western blot testing of anti-Caspase-8 antibody and Lane 1: rat thymus; 2: rat liver; 3: MCF-7; 4: HeLa; 5: SMMC-7721 (Caspase 8 抗体 (AA 240-259))

Western blot testing of anti-Caspase-8 antibody and Lane 1: rat thymus (Caspase 8 抗体 (AA 240-259))

2 images

产品编号 ABIN3030316

发货至: 中国

Quick Overview for Caspase 8 抗体 (AA 240-259) (ABIN3030316)

抗原

See all Caspase 8 (CASP8) 抗体

Caspase 8 (CASP8)

适用

140
69
62
23
16
16
11
1
1

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

102
17
11
4
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1

This Caspase 8 antibody is un-conjugated

应用范围

150
55
47
41
29
27
26
23
23
20
8
4
4
3
1
1
1
1

Western Blotting (WB)

Discover our top product CASP8 Primary Antibody

抗原表位
16

16

9

7

7

7

6

6

5

4

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 240-259

纯化方法

Antigen affinity

免疫原

Amino acids 240-259 (DKVYQMKSKPRGYCLIINNH-human) were used as the immunogen for this anti-Caspase-8 antibody. This sequence is from the large subunit.

亚型

IgG
anti-Caspase 8 (CASP8) (AA 411-482) antibody
CASP8 适用: 人, 小鼠, 大鼠, 猴, Pig, 绵羊 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Caspase 8 (CASP8) (AA 1-479) antibody
CASP8 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Caspase 8 (CASP8) (AA 188-280) antibody
CASP8 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Caspase 8 (CASP8) (AA 217-384) antibody
CASP8 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Caspase 8 (CASP8) (AA 7-201) antibody
CASP8 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Caspase 8 (CASP8) (AA 385-479) antibody
CASP8 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Caspase 8 (CASP8) antibody
CASP8 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 1H11 unconjugated

anti-Caspase 8 (CASP8) (AA 410-449), (N-Term) antibody
CASP8 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Caspase 8 (CASP8) (AA 217-374) antibody
CASP8 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Caspase 8 (CASP8) antibody
CASP8 适用: 小鼠 WB, IHC, ELISA, ICC, FACS 宿主: 大鼠 Monoclonal 3B10 unconjugated

应用备注

The stated application concentrations are suggested starting points. Titration of the anti-Caspase-8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

限制

仅限研究用
缓冲液

0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

储存条件

-20 °C

储存方法

After reconstitution, the anti-Caspase-8 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
抗原

Caspase 8 (CASP8)

别名

Caspase-8

背景

Most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death. Binding to the adapter molecule FADD recruits it to either receptor. The resulting aggregate called death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. The active dimeric enzyme is then liberated from the DISC and free to activate downstream apoptotic proteases including CASP3/4/6/7/9/10. [UniProt]

UniProt

Q14790

途径

Apoptosis, Caspase Cascade in Apoptosis, TLR signaling, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades

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