ABCC4 抗体 (AA 1-370)
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- 抗原 See all ABCC4 抗体
- ABCC4 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4))
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抗原表位
- AA 1-370
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ABCC4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- Antigen affinity
- 免疫原
- Human partial recombinant protein (AA 1-370) was used as the immunogen for this MRP4 antibody.
- 亚型
- IgG
- Top Product
- Discover our top product ABCC4 Primary Antibody
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anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4) (AA 631-692) antibody
ABCC4 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 2D2A9 unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4) (C-Term) antibodyVerified ABCC4 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4) (AA 1-110) antibodyABCC4 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1B2 unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4) (AA 495-705) antibodyABCC4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4) (AA 1-370) antibodyABCC4 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4) (AA 751-880) antibodyABCC4 适用: 人 ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4) antibodyABCC4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4) (AA 1041-1274) antibodyABCC4 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4) (AA 562-697) antibodyABCC4 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4) (AA 70-82) antibodyVerified ABCC4 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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- 应用备注
- Titration of the MRP4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
- 限制
- 仅限研究用
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- 缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- 储存条件
- -20 °C
- 储存方法
- The lyophilized MRP4 antibody can be stored at 4°C to -20°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- 抗原
- ABCC4 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4))
- 别名
- MRP4 (ABCC4 产品)
- 别名
- EST170205 antibody, MOAT-B antibody, MOATB antibody, MRP4 antibody, D630049P08Rik antibody, Mrp4 antibody, ATP binding cassette subfamily C member 4 antibody, multidrug resistance-associated protein 4 antibody, ATP-binding cassette, sub-family C (CFTR/MRP), member 4 antibody, ABCC4 antibody, LOC515333 antibody, LOC616707 antibody, LOC695407 antibody, abcc4 antibody, Abcc4 antibody
- 背景
- ABCC4 (ATP-binding cassette, subfamily c, member 4) also known as MRP4 (Multidrug resistance associated protein 4) or MOATB, is a protein that in humans is encoded by the ABCC4 gene. It belongs to a large family of transmembrane proteins involved in active transport of substrates out of cells. This gene is mapped to chromosome 13q32. ABCC4/MRP4 acts as an independent regulator of intracellular cyclic nucleotide levels and as a mediator of cAMP-dependent signal transduction to the nucleus. The antiproliferative effect of MPR4 inhibition was related to cAMP-dependent PKA activation and CREB phosphorylation. Pharmacologic inhibition of its activity or knockdown of the protein via RNA interference resulted in reduced migration of DCs from human skin explants and of in vitro-generated Langerhans cells. It has been found that MRP4 contributes to migration of DCs toward draining lymph nodes and therefore has a role in the initiation of an immune response.
- 基因ID
- 10257
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