ABCC4 抗体 (AA 1-370)
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- 抗原 See all ABCC4 抗体
- ABCC4 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4))
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抗原表位
- AA 1-370
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ABCC4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Multidrug resistance-associated protein 4(ABCC4) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Multidrug resistance-associated protein 4(ABCC4) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 4
Protein Name: Multidrug resistance-associated protein 4 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human MRP4 recombinant protein (Position: M1-P370).
- 亚型
- IgG
- Top Product
- Discover our top product ABCC4 Primary Antibody
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anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4) (AA 631-692) antibody
ABCC4 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 2D2A9 unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4) (C-Term) antibodyVerified ABCC4 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4) (AA 1-110) antibodyABCC4 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1B2 unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4) (AA 495-705) antibodyABCC4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4) (AA 751-880) antibodyABCC4 适用: 人 ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4) antibodyABCC4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4) (AA 1041-1274) antibodyABCC4 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4) (AA 562-697) antibodyABCC4 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4) (AA 70-82) antibodyVerified ABCC4 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4) (AA 1231-1280) antibodyABCC4 适用: 人, 马, 兔, 豚鼠, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for MRP4 is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- ABCC4 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4))
- 别名
- ABCC4 (ABCC4 产品)
- 别名
- EST170205 antibody, MOAT-B antibody, MOATB antibody, MRP4 antibody, D630049P08Rik antibody, Mrp4 antibody, ATP binding cassette subfamily C member 4 antibody, multidrug resistance-associated protein 4 antibody, ATP-binding cassette, sub-family C (CFTR/MRP), member 4 antibody, ABCC4 antibody, LOC515333 antibody, LOC616707 antibody, LOC695407 antibody, abcc4 antibody, Abcc4 antibody
- 背景
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ABCC4(Atp-binding cassette, subfamily c, member 4) also known as MRP4 or MOATB, is a protein that in humans is encoded by the ABCC4 gene. It belongs to a large family of transmembrane proteins involved in active transport of substrates out of cells. This gene is mapped to chromosome 13q32. ABCC4 acts as an independent regulator of intracellular cyclic nucleotide levels and as a mediator of cAMP-dependent signal transduction to the nucleus. The antiproliferative effect of ABCC4 inhibition was related to cAMP-dependent PKA activation and CREB phosphorylation. Pharmacologic inhibition of ABCC4 activity or knockdown of ABCC4 via RNA interference resulted in reduced migration of DCs from human skin explants and of in vitro-generated Langerhans cells. It has been found that ABCC4 contributes to migration of DCs toward draining lymph nodes and therefore has a role in the initiation of an immune response.
Synonyms: ABCC 4 antibody|ABCC4 antibody|ATP binding cassette sub family C (CFTR/MRP) member 4 antibody|ATP binding cassette sub family C member 4 antibody|ATP-binding cassette sub-family C member 4 antibody|bA464I2.1 (ATP binding cassette, sub-family C (CFTR/MRP) member 4) antibody|bA464I2.1 antibody|Canalicular multispecific organic anion transporter ABC superfamily antibody|canalicular multispecific organic anion transporter antibodyEST170205 antibody|MOAT B antibody|MOAT-B antibody|MOATB antibody|MRP 4 antibody|MRP/cMOAT related ABC transporter antibody|MRP/cMOAT-related ABC transporter antibody|MRP4_HUMAN antibody|Multi specific organic anion transporter B antibody|Multi-specific organic anion transporter B antibody|Multidrug resistance associated protein 4 antibody|Multidrug resistance-associated protein 4 antibody|OTTHUMP00000018560 antibody - 基因ID
- 10257
- UniProt
- O15439
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