电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

RAGE 抗体 (Middle Region)

AGER 适用: 人, 小鼠, 大鼠 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3029885
发货至: 中国
  • 抗原 See all RAGE (AGER) 抗体
    RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
    抗原表位
    • 20
    • 16
    • 16
    • 11
    • 11
    • 9
    • 8
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 142
    • 82
    • 64
    • 8
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 137
    • 10
    • 4
    • 2
    • 1
    克隆类型
    • 131
    • 22
    • 1
    多克隆
    标记
    • 70
    • 11
    • 10
    • 9
    • 8
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This RAGE antibody is un-conjugated
    应用范围
    • 126
    • 65
    • 49
    • 33
    • 27
    • 26
    • 24
    • 11
    • 8
    • 7
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    纯化方法
    Antigen affinity
    免疫原
    An amino acid sequence from the middle region of human RAGE (KEQTRRHPETGLFTLQSEL) was used as the immunogen for this RAGE antibody.
    亚型
    IgG
    Top Product
    Discover our top product AGER Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the RAGE antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the RAGE antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
    别名
    RAGE (AGER 产品)
    别名
    RAGE antibody, AGER antibody, advanced glycosylation end-product specific receptor antibody, advanced glycosylation end product-specific receptor antibody, MAPK/MAK/MRK overlapping kinase antibody, AGER antibody, Ager antibody, LOC719012 antibody
    背景
    The receptor for advanced glycation end products(RAGE) is a multi-ligand member of the immunoglobulin superfamily of cell surface molecules. It interacts with distinct molecules implicated in homeostasis, development and inflammation, and certain diseases such as diabetes and Alzheimers disease. RAGE is also a central cell surface receptor for amphoterin and EN-RAGE. RAGE is associated with sustained NF-kappaB activation in the diabetic microenvironment and has a central role in sensory neuronal dysfunction. Moreover, RAGE propagates cellular dysfunction in several inflammatory disorders and diabetes, and it also functions as an endothelial adhesion receptor promoting leukocyte recruitment.
    UniProt
    Q15109
    途径
    Carbohydrate Homeostasis, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, S100 Proteins
You are here:
客服