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CSF3R 抗体 (Middle Region)

CSF3R 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3029704
发货至: 中国
  • 抗原 See all CSF3R 抗体
    CSF3R (Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R))
    抗原表位
    • 12
    • 7
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    Middle Region
    适用
    • 65
    • 25
    • 22
    • 1
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    • 1
    • 1
    宿主
    • 55
    • 11
    • 2
    • 1
    • 1
    克隆类型
    • 59
    • 11
    多克隆
    标记
    • 32
    • 7
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    • 1
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    • 1
    • 1
    • 1
    • 1
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    This CSF3R antibody is un-conjugated
    应用范围
    • 59
    • 27
    • 19
    • 17
    • 9
    • 6
    • 4
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    • 2
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    • 1
    Western Blotting (WB)
    纯化方法
    Antigen affinity
    免疫原
    An amino acid sequence from the middle region of human CSF3R (EPWQPGLHINQKCELRHK) was used as the immunogen for this CSF3R antibody.
    亚型
    IgG
    Top Product
    Discover our top product CSF3R Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the CSF3R antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the CSF3R antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    CSF3R (Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R))
    别名
    CSF3R Colony Stimulating Factor 3 Receptor (CSF3R 产品)
    别名
    CD114 antibody, GCSFR antibody, Cd114 antibody, Csfgr antibody, G-CSF-R antibody, G-CSFR antibody, CSF3R antibody, gcsfr antibody, cd114 antibody, colony stimulating factor 3 receptor antibody, colony stimulating factor 3 receptor (granulocyte) antibody, colony stimulating factor 3 receptor L homeolog antibody, granulocyte colony-stimulating factor receptor antibody, CSF3R antibody, Csf3r antibody, csf3r antibody, csf3r.L antibody, LOC100433338 antibody
    背景
    Colony-Stimulating Factor 3 Receptor, Granulocyte also known as GCSFR or CD114 (Cluster of Differentiation 114) is a protein that in humans is encoded by the CSF3R gene. G-CSF-R is a cell-surface receptor for the granulocyte colony-stimulating factor (G-CSF). The G-CSF receptors belongs to a family of cytokine receptors known as the hematopoietin receptor family. By in situ hybridization using human CSF3R cDNA as a probe, Inazawa et al.(1991) localized the gene to 1p35-p34.3. The G-CSF-R is a transmembrane receptor that consists of an extracellular ligand-binding portion, a transmembrane domain, and the cytoplasmic portion that is responsible for signal transduction. GCSF-R ligand-binding is associated with dimerization of the receptor and signal transduction through proteins including Jak, Lyn, STAT, and Erk1/2. Dong et al.(2001) reported that the C terminus of CSF3R is required for SHP1 downregulation of CSF3-induced STAT activation. The authors proposed that this mechanism inhibits cell proliferation and survival in response to CSF3.
    UniProt
    Q99062
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