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TSC1 抗体 (C-Term)

TSC1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3029309
发货至: 中国
  • 抗原 See all TSC1 抗体
    TSC1 (Tuberous Sclerosis 1 (TSC1))
    抗原表位
    • 24
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    C-Term
    适用
    • 188
    • 139
    • 53
    • 24
    • 18
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 302
    • 16
    • 1
    • 1
    克隆类型
    • 304
    • 16
    多克隆
    标记
    • 114
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    • 32
    • 3
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    This TSC1 antibody is un-conjugated
    应用范围
    • 230
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    • 92
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    • 16
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Antigen affinity
    免疫原
    An amino acid sequence from the C-terminus of human Tuberous Sclerosis 1 (QLHIMDYNETHHEHS) was used as the immunogen for this TSC1 antibody (100% rat homology).
    亚型
    IgG
    Top Product
    Discover our top product TSC1 Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the TSC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the TSC1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    TSC1 (Tuberous Sclerosis 1 (TSC1))
    别名
    TSC1 (Hamartin) (TSC1 产品)
    别名
    LAM antibody, TSC antibody, hamartin antibody, mKIAA0243 antibody, tsc1 antibody, wu:fc38b04 antibody, fa99f04 antibody, wu:fa99f04 antibody, zgc:63657 antibody, TSC complex subunit 1 antibody, tuberous sclerosis 1 antibody, TSC complex subunit 1b antibody, TSC complex subunit 1a antibody, TSC1 antibody, Tsc1 antibody, tsc1b antibody, tsc1 antibody, tsc1a antibody
    背景
    TSC1 (Tuberous Sclerosis 1), also called Hamartin, is a human protein and gene. As part of a comprehensive strategy to identify the gene mutant in tuberous sclerosis-1, van Slegtenhorst et al.(1997) developed an overlapping contig of clones from the 1.4-Mb TSC1 region on chromosome 9. Benvenuto et al.(2000) showed that overexpression of the TSC1 gene in rat fibroblasts inhibits growth and causes changes in cell morphology. Van Slegtenhorst et al.(1998) showed that hamartin and tuberin associate physically in vivo, however, and that the interaction is mediated by predicted coiled-coil domains.
    UniProt
    Q92574
    途径
    RTK signaling, AMPK Signaling, Regulation of Cell Size, Tube Formation
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