TRPC3 抗体 (AA 836-851)
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- 抗原 See all TRPC3 抗体
- TRPC3 (Transient Receptor Potential Cation Channel, Subfamily C, Member 3 (TRPC3))
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抗原表位
- AA 836-851
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TRPC3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- Antigen affinity
- 免疫原
- Amino acids 836-851 (HSFNSILNQPTRYQQI) were used as the immunogen for this TRPC3 antibody (100% homologous in human, mouse and rat).
- 亚型
- IgG
- Top Product
- Discover our top product TRPC3 Primary Antibody
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anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 3 (TRPC3) (AA 822-835), (C-Term), (Intracellular) antibody
TRPC3 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IP, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 3 (TRPC3) (N-Term) antibodyTRPC3 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 3 (TRPC3) (AA 485-535) antibodyTRPC3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 3 (TRPC3) (AA 822-835), (C-Term), (Intracellular) antibody (Atto 594)TRPC3 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal Atto 594
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 3 (TRPC3) (N-Term) antibodyTRPC3 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 3 (TRPC3) (N-Term) antibodyTRPC3 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 3 (TRPC3) (C-Term) antibodyTRPC3 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- The stated application concentrations are suggested starting amounts. Titration of the TRPC3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
- 限制
- 仅限研究用
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- 缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- 储存条件
- -20 °C
- 储存方法
- After reconstitution, the TRPC3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- 抗原
- TRPC3 (Transient Receptor Potential Cation Channel, Subfamily C, Member 3 (TRPC3))
- 别名
- TRPC3 (TRPC3 产品)
- 别名
- TRPC3 antibody, Trpc3 antibody, TRP3 antibody, Mwk antibody, Trcp3 antibody, Trp3 antibody, Trrp3 antibody, TrpC3c antibody, transient receptor potential cation channel subfamily C member 3 antibody, transient receptor potential cation channel, subfamily C, member 3 antibody, TRPC3 antibody, Trpc3 antibody
- 背景
- Transient receptor potential cation channel, subfamily C, member 3, also known as TRP3, is expressed in megakaryocytic cell lines and therefore may play a role in calcium homeostasis in megakaryocytes and platelets. Using patch-clamp and whole-cell recordings of human embryonic kidney cells transfected with TRPC3, the protein behaved as an inositol phosphate and diacylglycerol-gated channel, but not as a store-operated channel. The TRPC3 gene, but not other TRPC genes, was damaged in several mutant T-cell lines with defective calcium influx, resulting in expression of truncated transcripts. Reduced calcium channel activity could be reversed by restoration of wildtype TRPC3. It is part of endogenous calcium channels in T lymphocytes and contributes to T-cell receptor-dependent calcium entry into T cells. Neuropathologic studies showed impaired growth and differentiation of dendritic arbors of the Purkinje cells, suggesting that normal TRPC3 plays a role in the development and survival of cerebellar Purkinje cells.
- UniProt
- Q13507
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