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TRPC3 产品

(Transient Receptor Potential Cation Channel, Subfamily C, Member 3 (TRPC3))

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The protein encoded by this gene is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].

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Featured TRPC3 Categories

TRPC3 抗体

High quality antibodies with extensive validation data.

TRPC3 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TRPC3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF, IP, ICC, FACS
Validations
  • (6)
Cat. No. ABIN7043820
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (3)
  • (2)
Cat. No. ABIN541552
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN563263
Quantity 50 μL
Datasheet Datasheet

Recommended TRPC3 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1323818
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3074938
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3130595
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our TRPC3 Products

Andrikopoulos, Eccles, Yaqoob: "Coupling between the TRPC3 ion channel and the NCX1 transporter contributed to VEGF-induced ERK1/2 activation and angiogenesis in human primary endothelial cells." in: Cellular signalling, Vol. 37, pp. 12-30, (2017) (PubMed).

Álvarez-Miguel, Cidad, Pérez-García, López-López: "Differences in TRPC3 and TRPC6 channels assembly in mesenteric vascular smooth muscle cells in essential hypertension." in: The Journal of physiology, (2016) (PubMed).

Sinai, Ivakine, Lam, Deurloo, Dida, Zirngibl, Jung, Aubin, Feng, Yeomans, McInnes, Osborne, Roder: "Disruption of Src Is Associated with Phenotypes Related to Williams-Beuren Syndrome and Altered Cellular Localization of TFII-I(1,2)." in: eNeuro, Vol. 2, Issue 2, (2015) (PubMed).

Ishise, Larson, Hirata, Fujiwara, Nishimoto, Kubo, Matsuda, Kanazawa, Sotsuka, Fujita, Kakibuchi, Kawai: "Hypertrophic scar contracture is mediated by the TRPC3 mechanical force transducer via NFkB activation." in: Scientific reports, Vol. 5, pp. 11620, (2015) (PubMed).

Li, Ding, Lopez, Takeshima, Ma, Allen, Eltit: "Impaired Orai1-mediated resting Ca2+ entry reduces the cytosolic [Ca2+] and sarcoplasmic reticulum Ca2+ loading in quiescent junctophilin 1 knock-out myotubes." in: The Journal of biological chemistry, Vol. 285, Issue 50, pp. 39171-9, (2010) (PubMed).

Li, Calfa, Inoue, Amaral, Pozzo-Miller: "Activity-dependent release of endogenous BDNF from mossy fibers evokes a TRPC3 current and Ca2+ elevations in CA3 pyramidal neurons." in: Journal of neurophysiology, Vol. 103, Issue 5, pp. 2846-56, (2010) (PubMed).

Aydar, Yeo, Djamgoz, Palmer et al.: "Abnormal expression, localization and interaction of canonical transient receptor potential ion channels in human breast cancer cell lines and tissues: a potential target for breast cancer diagnosis ..." in: Cancer cell international, Vol. 9, pp. 23, (2009) (PubMed).

Cohen, Torres, Ma, Holowka, Baird: "Ca2+ waves initiate antigen-stimulated Ca2+ responses in mast cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 10, pp. 6478-88, (2009) (PubMed).

Dietrich, Kalwa, Rost, Gudermann: "The diacylgylcerol-sensitive TRPC3/6/7 subfamily of cation channels: functional characterization and physiological relevance." in: Pflügers Archiv : European journal of physiology, Vol. 451, Issue 1, pp. 72-80, (2005) (PubMed).

Kim, Kim, Lee, Lim, Cho, Yoon, Cho, Baek, Park, Paik, Choe, Lee: "Up-regulation of Bfl-1/A1 via NF-kappaB activation in cisplatin-resistant human bladder cancer cell line." in: Cancer letters, Vol. 212, Issue 1, pp. 61-70, (2004) (PubMed).

Synonyms and alternative names related to TRPC3

transient receptor potential cation channel subfamily C member 3 (TRPC3), transient receptor potential cation channel, subfamily C, member 3 (TRPC3), transient receptor potential cation channel subfamily C member 3 (Trpc3), transient receptor potential cation channel, subfamily C, member 3 (Trpc3), Mwk, Trcp3, TRP3, Trp3, TRPC3, Trpc3, TrpC3c, Trrp3

Protein level used designations for TRPC3

  • transient receptor potential cation channel, subfamily C, member 3
  • short transient receptor potential channel 3-like
  • short transient receptor potential channel 3
  • hTrp-3
  • transient receptor protein 3
  • TRP-3
  • mTrp3
  • receptor-activated cation channel TRP3
  • trp-related protein 3
  • ion channel protein
  • transient receptor potential cation channel subfamily C member 3
  • oocyte transient receptor potential channel
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