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SNAP23 抗体 (C-Term)

SNAP23 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3029070
发货至: 中国
  • 抗原 See all SNAP23 抗体
    SNAP23 (Synaptosomal-Associated Protein, 23kDa (SNAP23))
    抗原表位
    • 15
    • 9
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    • 5
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
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    • 1
    C-Term
    适用
    • 67
    • 19
    • 17
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
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    • 1
    人, 小鼠, 大鼠
    宿主
    • 62
    • 4
    • 2
    • 1
    • 1
    克隆类型
    • 58
    • 12
    多克隆
    标记
    • 34
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    This SNAP23 antibody is un-conjugated
    应用范围
    • 41
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    • 13
    • 13
    • 13
    • 8
    • 7
    • 7
    • 5
    • 2
    • 1
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    纯化方法
    Antigen affinity
    免疫原
    An amino acid sequence from the C-terminus of human SNAP23 (DTNRDRIDIANARAKKLIDS) was used as the immunogen for this SNAP23 antibody.
    亚型
    IgG
    Top Product
    Discover our top product SNAP23 Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the SNAP23 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the SNAP23 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    SNAP23 (Synaptosomal-Associated Protein, 23kDa (SNAP23))
    别名
    SNAP23 (SNAP23 产品)
    别名
    23kDa antibody, AA408749 antibody, SNAP-23 antibody, Sndt antibody, Syndet antibody, HsT17016 antibody, SNAP23A antibody, SNAP23B antibody, XOSNAP-23 antibody, snap23-A antibody, synaptosome associated protein 23 antibody, synaptosome associated protein 23kDa antibody, synaptosomal-associated protein 23 antibody, synaptosome associated protein 23kDa L homeolog antibody, SNAP23 antibody, snap23 antibody, Snap23 antibody, snap23.L antibody
    背景
    Synaptosomal-Associated Protein, 23-KD is a protein that in humans is encoded by the SNAP23 gene. The gene has 8 exons, with the initiation codon located in exon 2 and is mapped on 15q15.1-q15.2. Its amino acid sequence is 59 % identical to that of SNAP25. Northern blot analysis revealed that SNAP23 is ubiquitously expressed. The protein is able to bind to multiple syntaxins as well as to multiple vesicle-associated membrane proteins. After relocation, it is required for exocytosis, implying a crucial role in promoting membrane fusion. TIVAMP-containing vesicles were concentrated in the apical domain of epithelial cells. STX3A and SNAP23 were codistributed at the apical plasma membrane, where they formed N-ethyl maleimide-dependent SNARE complexes with TIVAMP and cellubrevin. It is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion.
    UniProt
    O00161
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