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SNAP23 抗体 (C-Term)

SNAP23 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044163
发货至: 中国
  • 抗原 See all SNAP23 抗体
    SNAP23 (Synaptosomal-Associated Protein, 23kDa (SNAP23))
    抗原表位
    • 15
    • 8
    • 8
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 192-211, C-Term
    适用
    • 66
    • 18
    • 16
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 61
    • 4
    • 2
    • 1
    • 1
    克隆类型
    • 57
    • 12
    多克隆
    标记
    • 33
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This SNAP23 antibody is un-conjugated
    应用范围
    • 40
    • 30
    • 27
    • 13
    • 13
    • 12
    • 7
    • 7
    • 7
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    原理
    Rabbit IgG polyclonal antibody for Synaptosomal-associated protein 23(SNAP23) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.
    序列
    DTNRDRIDIA NARAKKLIDS
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Synaptosomal-associated protein 23(SNAP23) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.
    Gene Name: synaptosomal-associated protein, 23 kDa
    Protein Name: Synaptosomal-associated protein 23(SNAP-23)
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human SNAP23(192-211aa DTNRDRIDIANARAKKLIDS), different from the related rat and mouse sequences by three amino acids.
    亚型
    IgG
    Top Product
    Discover our top product SNAP23 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Predicted Species: Rat
    ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • 抗原
    SNAP23 (Synaptosomal-Associated Protein, 23kDa (SNAP23))
    别名
    SNAP23 (SNAP23 产品)
    别名
    23kDa antibody, AA408749 antibody, SNAP-23 antibody, Sndt antibody, Syndet antibody, HsT17016 antibody, SNAP23A antibody, SNAP23B antibody, XOSNAP-23 antibody, snap23-A antibody, synaptosome associated protein 23 antibody, synaptosome associated protein 23kDa antibody, synaptosomal-associated protein 23 antibody, synaptosome associated protein 23kDa L homeolog antibody, SNAP23 antibody, snap23 antibody, Snap23 antibody, snap23.L antibody
    背景
    SNAP23(Synaptosomal-Associated Protein, 23-KD), also called SNAP23A, is a protein that in humans is encoded by the SNAP23 gene. The SNAP23 gene has 8 exons, with the initiation codon located in exon 2. The SNAP23 gene is mapped on 15q15.1-q15.2. The SNAP23 cDNA encodes a 211-amino acid polypeptide with a predicted mass of 23 kD. Its amino acid sequence is 59 % identical to that of SNAP25. Northern blot analysis revealed that SNAP23 is ubiquitously expressed. SNAP23 is able to bind to multiple syntaxins as well as to multiple vesicle-associated membrane proteins. After relocation, SNAP23 is required for exocytosis, implying a crucial role in promoting membrane fusion. TIVAMP-containing vesicles were concentrated in the apical domain of epithelial cells. STX3A and SNAP23 were codistributed at the apical plasma membrane, where they formed N-ethyl maleimide-dependent SNARE complexes with TIVAMP and cellubrevin. SNAP23 is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion.

    Synonyms: HsT17016 antibody|LS-B8340 antibody|SNAP 23 antibody|SNAP-23 antibody|SNAP23 antibody|SNAP23A antibody|SNAP23B antibody|SNP23_HUMAN antibody|Synaptosomal associated protein 23 antibody|Synaptosomal associated protein 23 kDa antibody|Synaptosomal associated protein antibody|Synaptosomal-associated protein 23 antibody|Vesicle membrane fusion protein SNAP 23 antibody|Vesicle membrane fusion protein SNAP23 antibody|Vesicle-membrane fusion protein SNAP-23 antibody
    UniProt
    O00161
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