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Cytokeratin 18 抗体

KRT18 适用: 人, 犬, Cat IHC (p) 宿主: 小鼠 Monoclonal DE-K18 unconjugated
产品编号 ABIN3026959
发货至: 中国
  • 抗原 See all Cytokeratin 18 (KRT18) 抗体
    Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
    适用
    • 252
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    人, 犬, Cat
    宿主
    • 165
    • 122
    • 3
    • 1
    • 1
    小鼠
    克隆类型
    • 151
    • 141
    单克隆
    标记
    • 144
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    This Cytokeratin 18 antibody is un-conjugated
    应用范围
    • 217
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    • 40
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    • 27
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    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    无交叉反应
    大鼠
    产品特性
    This mAb reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It was reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.
    纯化方法
    Protein G affinity chromatography
    免疫原
    A cytoskeletal preparation from A431 cells was used as the immunogen for the Cytokeratin 18 antibody.
    克隆位点
    DE-K18
    亚型
    IgG1 kappa
    Top Product
    Discover our top product KRT18 Primary Antibody
  • 应用备注
    Optimal dilution of the Cytokeratin 18 antibody should be determined by the researcher.

    1. Staining of formalin-fixed tissues requires boiling tissue sections in 10  mM Citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min
    2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Prediluted IHC only format : incubate for 30 min at RT (2)

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, *For IHC use only*
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store the Cytokeratin 18 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原
    Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
    别名
    Cytokeratin 18 (KRT18 产品)
    别名
    CK18 antibody, K18 antibody, Krt1-18 antibody, CYK18 antibody, DreK18 antibody, cb83 antibody, dapk1 antibody, sb:cb83 antibody, wu:fa13f02 antibody, wu:fb36b04 antibody, krt18 antibody, MGC64569 antibody, MGC75922 antibody, KRT18 antibody, CK-18-A antibody, K18-A antibody, NC-11 antibody, cyk18 antibody, k18 antibody, krt18-a antibody, krt18-b antibody, krt18a antibody, xkendob antibody, keratin 18 antibody, keratin 18, type I L homeolog antibody, keratin 18, type I antibody, keratin, type I cytoskeletal 18 antibody, K18, simple type I keratin antibody, Keratin, type I cytoskeletal 18 antibody, keratin 18, type I S homeolog antibody, Krt18 antibody, KRT18 antibody, krt18 antibody, krt18.L antibody, LOC700569 antibody, LOC100136778 antibody, k1c18 antibody, LOC100008885 antibody, krt18.S antibody
    背景
    This mAb reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It was reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.
    途径
    Apoptosis, Caspase Cascade in Apoptosis
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