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CD28 抗体

CD28 适用: 人, 小鼠, Cow, Pig, 绵羊 FACS, IF, Func 宿主: 小鼠 Monoclonal 204-12 unconjugated
产品编号 ABIN3025652
发货至: 中国
  • 抗原 See all CD28 抗体
    CD28
    适用
    • 173
    • 128
    • 58
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    人, 小鼠, Cow, Pig, 绵羊
    宿主
    • 126
    • 79
    • 33
    • 16
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    小鼠
    克隆类型
    • 188
    • 74
    • 3
    单克隆
    标记
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    This CD28 antibody is un-conjugated
    应用范围
    • 199
    • 94
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    Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)
    纯化方法
    Protein G affinity chromatography
    免疫原
    Stimulated human leukocytes were used as the immunogen for the CD28 antibody.
    克隆位点
    204-12
    亚型
    IgG2a kappa
    Top Product
    Discover our top product CD28 Primary Antibody
  • 应用备注
    Optimal dilution of the CD28 antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,Functional Activity (Order SAF formulation)
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store the CD28 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原
    CD28
    别名
    CD28 (CD28 产品)
    别名
    Tp44 antibody, CD28RNA antibody, cd28 antibody, CD28 molecule antibody, CD28 antigen antibody, Cd28 molecule antibody, CD28 molecule L homeolog antibody, CD28 antibody, Cd28 antibody, cd28.L antibody
    背景
    Recognizes a glycoprotein of 44-88  kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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