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CD28 抗体

CD28 适用: 人, 小鼠, Cow, Pig, 绵羊 FACS, IF, Func 宿主: 小鼠 Monoclonal 204-12 unconjugated
产品编号 ABIN6941133
发货至: 中国
  • 抗原 See all CD28 抗体
    CD28
    适用
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    人, 小鼠, Cow, Pig, 绵羊
    宿主
    • 125
    • 79
    • 33
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    小鼠
    克隆类型
    • 187
    • 74
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    单克隆
    标记
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    This CD28 antibody is un-conjugated
    应用范围
    • 198
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    Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)
    特异性
    Recognizes a glycoprotein of 44-88 kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.
    纯化方法
    Purified by Protein A/G
    免疫原
    Stimulated human leucocytes
    克隆位点
    204-12
    亚型
    IgG2a kappa
    Top Product
    Discover our top product CD28 Primary Antibody
  • 应用备注

    Positive Control: Jurkat cells. Human lymph nodes and tonsils.

    Known Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL) Functional Studies (Order Ab without BSA & Azide), Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    CD28
    别名
    CD28 (CD28 产品)
    别名
    Tp44 antibody, CD28RNA antibody, cd28 antibody, CD28 molecule antibody, CD28 antigen antibody, Cd28 molecule antibody, CD28 molecule L homeolog antibody, CD28 antibody, Cd28 antibody, cd28.L antibody
    分子量
    44kDa (monomer), 88kDa (dimer)
    基因ID
    940
    UniProt
    P10747
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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