TRIM29 抗体 (AA 1-200)
Quick Overview for TRIM29 抗体 (AA 1-200) (ABIN3025033)
抗原
See all TRIM29 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-200
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产品特性
- It recognizes a 66 kDa protein, which is identified as Tripartite motif-containing protein 29 (TRIM29). It interacts with the intermediate filament protein vimentin, a substrate for the PKC family of protein kinases, and with hPKCI-1, an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs, suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer, and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ~90 % positive accuracy, when used in a panel with TTF-1, p63, CK5/6, and Napsin-A antibodies.
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纯化方法
- Protein G affinity chromatography
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免疫原
- A recombinant fragment (126 amino acid residues between aa 1-200) of human TRIM29 protein was used as the immunogen for the TRIM29 antibody.
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亚型
- IgG2a kappa
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anti-Tripartite Motif Containing 29 (TRIM29) (AA 451-588) antibody
TRIM29 适用: 人 WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 8C8G5 unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (Internal Region) antibodyVerified TRIM29 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (AA 1-200) antibodyTRIM29 适用: 人 ELISA, IHC, Coat, StM 宿主: 小鼠 Monoclonal TRIM29-1041 unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (Internal Region) antibodyTRIM29 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (AA 1-200) antibodyTRIM29 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-629M unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (AA 309-588) antibodyTRIM29 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (C-Term) antibodyTRIM29 适用: 人, 小鼠, 大鼠, Cow, 马, 豚鼠, 犬, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (AA 1-588) antibodyTRIM29 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (AA 1-200) antibodyTRIM29 适用: 人 WB, ELISA, Coat 宿主: 小鼠 Monoclonal TRIM29-1042 unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (AA 253-283) antibodyTRIM29 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Optimal dilution of the TRIM29 antibody should be determined by the researcher.
1. Staining of formalin/paraffin tissues requires boiling tissue sections in 10 mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1),Prediluted format : incubate for 30 min at RT (2) -
限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the TRIM29 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- TRIM29 (Tripartite Motif Containing 29 (TRIM29))
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别名
- TRIM29
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背景
- It recognizes a 66 kDa protein, which is identified as Tripartite motif-containing protein 29 (TRIM29). It interacts with the intermediate filament protein vimentin, a substrate for the PKC family of protein kinases, and with hPKCI-1, an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs, suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer, and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ~90 % positive accuracy, when used in a panel with TTF-1, p63, CK5/6, and Napsin-A antibodies.
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途径
- p53 Pathway, Apoptosis, DNA Damage Repair, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
抗原
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