ATF6 抗体 (N-Term)
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- 抗原 See all ATF6 抗体
- ATF6 (Activating Transcription Factor 6 (ATF6))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ATF6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- Protein G purified monoclonal antibody
- 免疫原
- A recombinant protein fragment from the N-terminal region of human ATF6 was used as the immunogen for this antibody.
- 克隆位点
- AF6229
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product ATF6 Primary Antibody
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anti-Activating Transcription Factor 6 (ATF6) (AA 1-190) antibody
ATF6 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 6 (ATF6) (AA 1-377) antibodyATF6 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 6 (ATF6) (AA 437-449) antibodyVerified ATF6 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Activating Transcription Factor 6 (ATF6) (AA 301-400) antibodyATF6 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 6 (ATF6) (AA 350-377) antibodyATF6 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB22035 unconjugated
anti-Activating Transcription Factor 6 (ATF6) (AA 350-377) antibodyATF6 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 6 (ATF6) (AA 423-646) antibodyATF6 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 6 (ATF6) (AA 91-193) antibodyATF6 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3D5 unconjugated
anti-Activating Transcription Factor 6 (ATF6) (N-Term) antibodyATF6 适用: 人, 小鼠 WB, ICC 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 6 (ATF6) (N-Term) antibodyATF6 适用: 人 WB, IP 宿主: 小鼠 Monoclonal 1-7 unconjugated
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- 应用备注
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ATF6 is a 670 amino acid protein that migrates in western blot between 70~90 kD due to glycosylation.
1. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.
2. ATF6 is seen in western blotting between 75~90KD.\. Western blot: 2-4 μg/mL (2),IHC (Paraffin): 5 μg/mL (1) - 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- 0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US source) and 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Aliquot the antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- 抗原
- ATF6 (Activating Transcription Factor 6 (ATF6))
- 别名
- ATF6 (ATF6 产品)
- 别名
- ATF-6-like antibody, GB16435 antibody, ATF6 antibody, Atf6 antibody, ATF6A antibody, 9130025P16Rik antibody, 9630036G24 antibody, AA789574 antibody, Atf6alpha antibody, ESTM49 antibody, activating transcription factor 6 antibody, uncharacterized LOC412432 antibody, activating transcription factor 6 S homeolog antibody, cyclic AMP-dependent transcription factor ATF-6 alpha antibody, ATF6 antibody, LOC412432 antibody, atf6.S antibody, LOC100122162 antibody, Atf6 antibody
- 背景
- ER stress can cause the accumulation of unfolded proteins and lead to the activation of the UPR (unfolded proetin response). Cells have developed an intracellular signaling pathway to deal with this stress, and Activating Transcription Factor 6 (ATF6) is a major transducer of the UPR. Upon activation, ATF6 seperates from GPR78 and is cleaved. The ~50 kD cytosolic portion of ATF6 translocates to the nucleus, transmitting the ER stress signal. In the nucleus, ATF6 activates the transcription of UPR-responsive genes by biniding to their ERSE (ER stress response element) region.
- 基因ID
- 22926
- 途径
- ER-Nucleus Signaling, Unfolded Protein Response
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