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CYLD 抗体

CYLD 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3024584
发货至: 中国
  • 抗原 See all CYLD 抗体
    CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))
    适用
    • 41
    • 24
    • 18
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 35
    • 6
    • 1
    克隆类型
    • 36
    • 6
    多克隆
    标记
    • 24
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CYLD antibody is un-conjugated
    应用范围
    • 33
    • 15
    • 8
    • 5
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Protein A affinity chromatography
    免疫原
    A recombinant protein fragment from the N-termiinal region of human CYLD was used as the immunogen for this antibody.
    亚型
    IgG
    Top Product
    Discover our top product CYLD Primary Antibody
  • 应用备注
    Provided assay concentrations are suggestions only, CYLD antibody titration may be required for optimal results.\. Western blot: 2-5 μg/mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the CYLD antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))
    别名
    CYLD (CYLD 产品)
    别名
    BRSS antibody, CDMT antibody, CYLD1 antibody, CYLDI antibody, EAC antibody, MFT antibody, MFT1 antibody, SBS antibody, TEM antibody, USPL2 antibody, 2010013M14Rik antibody, 2900009M21Rik antibody, C130039D01Rik antibody, mKIAA0849 antibody, cyld antibody, LRRGT00003 antibody, Rp1 antibody, Rp1h antibody, CYLD lysine 63 deubiquitinase antibody, cylindromatosis (turban tumor syndrome), a antibody, CYLD antibody, Cyld antibody, cylda antibody
    背景
    CYLD is involved in multiple physiological processes including immune response, osteoclastogenesis and spermatogenesis. It is a tumor suppressor via its negative regulation of NF-kB activation. CYLD is a deubiquitinase, removing ubiquitin chains from tumor-necrosis factor receptor-associated factor 2 (TRAF2) and thereby preventing its activation of IkB, a regulator of NF-kB. NF-kB remains sequestered in the cytoplasm, unable to translocate to the nucleus and initiate cell survival and oncogenetic signaling.
    基因ID
    1540
    途径
    Apoptosis, Activation of Innate immune Response
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