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CYLD 抗体
CYLD
适用: 人, 小鼠
WB
宿主: 兔
Polyclonal
unconjugated
CYLD抗体详情
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抗原
See all CYLD 抗体
CYLD
(Cylindromatosis (Turban Tumor Syndrome) (CYLD))
适用
All reactivities for CYLD 抗体
人, 小鼠
宿主
All hosts for CYLD 抗体
兔
克隆类型
All clonalities for CYLD 抗体
多克隆
标记
All conjugates for CYLD 抗体
This CYLD antibody is un-conjugated
应用范围
All applications for CYLD 抗体
Western Blotting (WB)
纯化方法
Protein A affinity chromatography
免疫原
A recombinant protein fragment from the N-termiinal region of human CYLD was used as the immunogen for this antibody.
亚型
IgG
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Discover our top product CYLD Primary Antibody
Alternatives
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anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 32-45) antibody
CYLD
适用: 人, 小鼠, Hamster, 猴, Cow, 豚鼠, 马, 小鸡, 兔, 犬
WB, ICC
宿主: 兔
Polyclonal
unconjugated
使用细节
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应用备注
Provided assay concentrations are suggestions only, CYLD antibody titration may be required for optimal results.\. Western blot: 2-5 μg/mL
限制
仅限研究用
贮存及处理
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浓度
0.5 mg/mL
缓冲液
0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Aliquot the CYLD antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
CYLD目标详情
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抗原
CYLD
(Cylindromatosis (Turban Tumor Syndrome) (CYLD))
别名
CYLD (CYLD 产品 )
别名
BRSS antibody, CDMT antibody, CYLD1 antibody, CYLDI antibody, EAC antibody, MFT antibody, MFT1 antibody, SBS antibody, TEM antibody, USPL2 antibody, 2010013M14Rik antibody, 2900009M21Rik antibody, C130039D01Rik antibody, mKIAA0849 antibody, cyld antibody, LRRGT00003 antibody, Rp1 antibody, Rp1h antibody, CYLD lysine 63 deubiquitinase antibody, cylindromatosis (turban tumor syndrome), a antibody, CYLD antibody, Cyld antibody, cylda antibody
背景
CYLD is involved in multiple physiological processes including immune response, osteoclastogenesis and spermatogenesis. It is a tumor suppressor via its negative regulation of NF-kB activation. CYLD is a deubiquitinase, removing ubiquitin chains from tumor-necrosis factor receptor-associated factor 2 (TRAF2) and thereby preventing its activation of IkB, a regulator of NF-kB. NF-kB remains sequestered in the cytoplasm, unable to translocate to the nucleus and initiate cell survival and oncogenetic signaling.
基因ID
1540
途径
Apoptosis , Activation of Innate immune Response
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