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CD46 抗体

CD46 适用: 人 FACS, IF 宿主: 小鼠 Monoclonal 122-2 unconjugated
产品编号 ABIN3024431
发货至: 中国
  • 抗原 See all CD46 抗体
    CD46
    适用
    • 111
    • 38
    • 20
    • 10
    • 10
    • 1
    宿主
    • 83
    • 48
    • 2
    小鼠
    克隆类型
    • 72
    • 61
    单克隆
    标记
    • 50
    • 17
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    This CD46 antibody is un-conjugated
    应用范围
    • 86
    • 75
    • 42
    • 40
    • 33
    • 15
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    • 9
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    Flow Cytometry (FACS), Immunofluorescence (IF)
    纯化方法
    Protein G affinity chromatography
    免疫原
    Recombinant human protein was used as the immunogen for this CD46 antibody.
    克隆位点
    122-2
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD46 Primary Antibody
  • 应用备注
    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CD46 antibody to be titered up or down for optimal performance.\. FACS: 0.5-1 μg/million cells,IF: 0.5-1 μg/mL
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store the CD46 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原
    CD46
    别名
    CD46 (CD46 产品)
    别名
    AHUS2 antibody, MCP antibody, MIC10 antibody, TLX antibody, TRA2.10 antibody, Mcp antibody, CD46 antibody, CD46 molecule antibody, CD46 antigen, complement regulatory protein antibody, CD46 molecule, complement regulatory protein antibody, membrane cofactor protein-like antibody, CD46 antibody, Cd46 antibody, LOC100341359 antibody, LOC103789310 antibody
    背景
    CD46 acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. It may be involved in the fusion of the spermatozoa with the oocyte during fertilization. CD46 acts as a co-stimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46.
    基因ID
    4179
    途径
    Regulation of Actin Filament Polymerization
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