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CD11b 抗体

ITGAM 适用: 人, 小鼠, 兔, Baboon, 猕猴, Chimpanzee, Cynomolgus FACS, IF, BR 宿主: 大鼠 Monoclonal M1-70 unconjugated
产品编号 ABIN3024273
发货至: 中国
  • 抗原 See all CD11b (ITGAM) 抗体
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    适用
    • 250
    • 159
    • 62
    • 32
    • 17
    • 16
    • 15
    • 13
    • 11
    • 7
    • 6
    • 5
    • 5
    • 2
    • 2
    • 1
    人, 小鼠, 兔, Baboon, 猕猴, Chimpanzee, Cynomolgus
    宿主
    • 132
    • 102
    • 94
    • 4
    • 1
    • 1
    大鼠
    克隆类型
    • 234
    • 96
    • 1
    单克隆
    标记
    • 111
    • 37
    • 29
    • 25
    • 19
    • 10
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
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    • 3
    • 3
    • 3
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    • 3
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    • 3
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD11b antibody is un-conjugated
    应用范围
    • 247
    • 81
    • 76
    • 70
    • 55
    • 36
    • 36
    • 25
    • 20
    • 19
    • 13
    • 13
    • 6
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    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), Blocking Reagent (BR)
    纯化方法
    Protein G affinity chromatography
    免疫原
    B10 mouse spleen cells enriched for T lymphocytes were used as the immunogen for this CD11b antibody.
    克隆位点
    M1-70
    亚型
    IgG2b kappa
    Top Product
    Discover our top product ITGAM Primary Antibody
  • 应用备注
    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CD11b antibody to be titered up or down for optimal performance.\. FACS: 0.5-1 μg/million cells,IF: 0.5-1 μg/mL,Functional Activity (Blocking): order BSA/azide free format
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store the CD11b antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    别名
    CD11b (ITGAM 产品)
    别名
    CD11b/CD18 antibody, CR3 antibody, CR3A antibody, Cd11b antibody, F730045J24Rik antibody, Ly-40 antibody, MAC1 antibody, Mac-1 antibody, Mac-1a antibody, CD11B antibody, MAC-1 antibody, MAC1A antibody, MO1A antibody, SLEB6 antibody, C3bi antibody, integrin subunit alpha M antibody, integrin alpha M antibody, integrin, alpha M (complement component 3 receptor 3 subunit) antibody, integrin alpha-M antibody, ITGAM antibody, Itgam antibody, LOC100351865 antibody
    背景
    CD11b is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin alpha-M (CD11b) combines with the Integrin beta-2 (CD18) to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin alpha-M/beta-2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.
    基因ID
    3684
    途径
    Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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