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Elastase 3B 抗体 (AA 82-238)

ELA3B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal CELA3B-1218 unconjugated
产品编号 ABIN3023785
发货至: 中国
  • 抗原 See all Elastase 3B (ELA3B) 抗体
    Elastase 3B (ELA3B) (Elastase 3B, Pancreatic (ELA3B))
    抗原表位
    • 54
    • 9
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 82-238
    适用
    • 81
    • 20
    • 19
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 55
    • 35
    小鼠
    克隆类型
    • 59
    • 31
    单克隆
    标记
    • 43
    • 15
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    This Elastase 3B antibody is un-conjugated
    应用范围
    • 61
    • 60
    • 45
    • 41
    • 39
    • 38
    • 8
    • 5
    • 4
    • 4
    • 4
    • 3
    Western Blotting (WB), ELISA
    无交叉反应
    大鼠
    产品特性
    This mAb recognizes a protein of ~30 kDa, identified as CELA3B (Chymotrypsin like elastase family member 3B), or Elastase 3B. Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six genes which encode the structurally similar proteins: Elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, 3B has little elastolytic activity. Like most of the human elastases, 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. It may also function in the intestinal transport and metabolism of cholesterol. Elastases 3A/B have been referred to as Protease E and as Elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays.
    纯化方法
    Protein G affinity chromatography
    免疫原
    A partial recombinant protein (aa 82-238) was used as the immunogen for the CELA3B antibody.
    克隆位点
    CELA3B-1218
    亚型
    IgG1 kappa
    Top Product
    Discover our top product ELA3B Primary Antibody
  • 应用备注
    Optimal dilution of the CELA3B antibody should be determined by the researcher.\. ELISA : 2-4 μg/mL, order BSA free format for coating,Western blot: 1-2 μg/mL
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store the CELA3B antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原
    Elastase 3B (ELA3B) (Elastase 3B, Pancreatic (ELA3B))
    别名
    CELA3B (ELA3B 产品)
    别名
    CBPP antibody, E1 antibody, EL-1 antibody, ELA3B antibody, 0910001F22Rik antibody, 2310074F01Rik antibody, AI504000 antibody, Ela3 antibody, Ela3b antibody, ela3b antibody, MGC82867 antibody, ELA1 antibody, Cela3b antibody, CELA3B antibody, chymotrypsin like elastase family member 3B antibody, chymotrypsin-like elastase family, member 3B antibody, elastase 3B, pancreatic antibody, proproteinase E antibody, chymotrypsin like elastase family member 3B L homeolog antibody, chymotrypsin-like elastase family member 3B antibody, CELA3B antibody, Cela3b antibody, ela3b antibody, LOC478196 antibody, cela3b.L antibody, LOC100717936 antibody, LOC100071692 antibody
    背景
    This mAb recognizes a protein of ~30  kDa, identified as CELA3B (Chymotrypsin like elastase family member 3B), or Elastase 3B. Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six genes which encode the structurally similar proteins: Elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, 3B has little elastolytic activity. Like most of the human elastases, 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. It may also function in the intestinal transport and metabolism of cholesterol. Elastases 3A/B have been referred to as Protease E and as Elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays.
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