ATF2 抗体 (AA 1-190)
Quick Overview for ATF2 抗体 (AA 1-190) (ABIN3023064)
抗原
See all ATF2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-190
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序列
- MKFKLHVNSA RQYKDLWNMS DDKPFLCTAP GCGQRFTNED HLAVHKHKHE MTLKFGPARN DSVIVADQTP TPTRFLKNCE EVGLFNELAS PFENEFKKAS EDDIKKMPLD LSPLATPIIR SKIEEPSVVE TTHQDSPLPH PESTTSDEKE VPLAQTAQPT SAIVRPASLQ VPNVLLTSSD SSVIIQQAVP
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human ATF2 (NP_001871.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Virus-Triggered ATP Release Limits Viral Replication through Facilitating IFN-β Production in a P2X7-Dependent Manner." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 199, Issue 4, pp. 1372-1381, (2017) (PubMed).
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: "Virus-Triggered ATP Release Limits Viral Replication through Facilitating IFN-β Production in a P2X7-Dependent Manner." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 199, Issue 4, pp. 1372-1381, (2017) (PubMed).
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- ATF2 (Activating Transcription Factor 2 (ATF2))
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别名
- ATF2
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背景
- This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro, thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene,CRE-BP1,CREB-2,CREB2,HB16,TREB7,ATF2,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,MAPK-JNK Signaling Pathway,MAPK-P38 Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,ATF2
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分子量
- 13- 15 kDa/23-24 kDa/35-54 kDa
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基因ID
- 1386
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UniProt
- P15336
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途径
- MAPK Pathway, RTK signaling, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades
抗原
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