Insulin 抗体 (AA 1-110)
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北京 101111
Quick Overview for Insulin 抗体 (AA 1-110) (ABIN3022885)
抗原
See all Insulin (INS) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-110
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序列
- MALWMRLLPL LALLALWGPD PAAAFVNQHL CGSHLVEALY LVCGERGFFY TPKTRREAED LQVGQVELGG GPGAGSLQPL ALEGSLQKRG IVEQCCTSIC SLYQLENYCN
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human INS (NP_000198.1).
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亚型
- IgG
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anti-Insulin (INS) (AA 46-59) antibody
INS 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Insulin (INS) antibodyINS 适用: 人 IHC, WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Insulin (INS) (AA 90-110) antibodyINS 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin (INS) (AA 25-110) antibodyINS 适用: 大鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin (INS) antibodyINS 适用: 人, 小鼠, Pig, Cow, 大鼠, 兔, 豚鼠, 犬, 猴, Cat, 小鸡, 驴, 山羊, Hamster, 马, 绵羊, Avian WB 宿主: 山羊 Polyclonal unconjugated
anti-Insulin (INS) (AA 25-110) antibodyINS 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin (INS) (AA 25-110) antibodyINS 适用: 人 IHC, WB, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Insulin (INS) (AA 25-54) antibodyINS 适用: Cow IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin (INS) antibodyINS 适用: 人 IHC, ELISA 宿主: 兔 Monoclonal 1F6 unconjugated Recombinant Antibody
anti-Insulin (INS) antibodyINS 适用: 人, 小鼠, Pig, Cow, 大鼠 IHC, ELISA, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal D3E7 unconjugated
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Adropin deficiency worsens HFD-induced metabolic defects." in: Cell death & disease, Vol. 8, Issue 8, pp. e3008, (2018) (PubMed).
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: "Adropin deficiency worsens HFD-induced metabolic defects." in: Cell death & disease, Vol. 8, Issue 8, pp. e3008, (2018) (PubMed).
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- Insulin (INS)
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别名
- INS
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背景
- After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants.,IDDM,IDDM1,IDDM2,ILPR,IRDN,MODY10,INS,Insulin,insulin,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,AMPK Signaling Pathway,Endocrine and metabolic diseases,Diabetes,Obesity,Immunology & Inflammation,NF-kB Signaling Pathway,Neuroscience,Stem Cells,Cardiovascular,Heart,Cardiovascular diseases,Heart disease,INS
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分子量
- 11 kDa/21 kDa
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基因ID
- 3630
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UniProt
- P01308
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途径
- NF-kappaB Signaling, RTK signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
抗原
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