IKK alpha 抗体 (C-Term)
Quick Overview for IKK alpha 抗体 (C-Term) (ABIN3022825)
抗原
See all IKK alpha (CHUK) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - C-Term
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序列
 - IWHLLKIACT QSSARSLVGS SLEGAVTPQT SAWLPPTSAE HDHSLSCVVT PQDGETSAQM IEENLNCLGH LSTIIHEANE EQGNSMMNLD WSWLTE
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交叉反应
 - 人, 小鼠, 大鼠
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产品特性
 - Polyclonal Antibodies
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纯化方法
 - Affinity purification
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免疫原
 - A synthetic peptide corresponding to a sequence within amino acids 650 to the C-terminus of human IKKalpha (NP_001269.3).
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亚型
 - IgG
 
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应用备注
 - WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200
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限制
 - 仅限研究用
 
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状态
 - Liquid
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缓冲液
 - PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
 - Avoid freeze / thaw cycles
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储存条件
 - -20 °C
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储存方法
 - Store at -20°C. Avoid freeze / thaw cycles.
 
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                                            : "Broadleaf Mahonia attenuates granulomatous lobular mastitis‑associated inflammation by inhibiting CCL‑5 expression in macrophages."    in: International journal of molecular medicine, Vol. 41, Issue 1, pp. 340-352, (2018)         (PubMed).        
: "TNFα-YAP/p65-HK2 axis mediates breast cancer cell migration." in: Oncogenesis, Vol. 6, Issue 9, pp. e383, (2017) (PubMed).
: "MiR-223 suppresses endometrial carcinoma cells proliferation by targeting IGF-1R." in: American journal of translational research, Vol. 6, Issue 6, pp. 841-9, (2015) (PubMed).
 
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                                            : "Broadleaf Mahonia attenuates granulomatous lobular mastitis‑associated inflammation by inhibiting CCL‑5 expression in macrophages."    in: International journal of molecular medicine, Vol. 41, Issue 1, pp. 340-352, (2018)         (PubMed).        
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- IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))
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别名
 - CHUK
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背景
 - This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.,CHUK,IKBKA,IKK-alpha,IKK1,IKKA,NFKBIKA,TCF16,IKK alpha,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Phosphorylation,Signal Transduction,Kinase,Serine/threonine kinases,PI3K-Akt Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Death Receptor Signaling Pathway,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,Cardiovascular,CHUK
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分子量
 - 84 kDa
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基因ID
 - 1147
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UniProt
 - O15111
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途径
 - PI3K-Akt Signaling, NF-kappaB Signaling, RTK signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
 
抗原
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