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IKK alpha 抗体 (C-Term)

Name: IKK alpha 抗体 (C-Term)
Brand: antibodies-online
SKU: ABIN3022825
Availability: OutOfStock

Cited in 3+ publications. This 兔多克隆 anti-IKK alpha antibody specifically detects IKK alpha in WB, IHC, IF 和 IP. The antibody is reactive with 人 samples.

Western blot analysis of extracts of various cell lines, using CHUK antibody. (IKK alpha 抗体 (C-Term))

Immunofluorescence analysis of U-2 OS cells using CHUK antibody (ABIN3022824, ABIN3022825, ABIN3022826 and ABIN6219246) at dilution of 1:100. (IKK alpha 抗体 (C-Term))

Immunofluorescence analysis of A549 cell using CHUK antibody. (IKK alpha 抗体 (C-Term))

Immunohistochemistry of paraffin-embedded rat brain using CHUK antibody. (IKK alpha 抗体 (C-Term))

IHC (p)

Immunohistochemistry of paraffin-embedded mouse kidney using CHUK antibody. (IKK alpha 抗体 (C-Term))

IHC (p)

Immunofluorescence analysis of A549 cells using CHUK antibody. (IKK alpha 抗体 (C-Term))

Immunoprecipitation analysis of 200 μg extracts of 293T cells using 3 μg IKKα antibody (ABIN3022824, ABIN3022825, ABIN3022826 and ABIN6219246). (IKK alpha 抗体 (C-Term))

Immunofluorescence analysis of NIH/3T3 cells using CHUK antibody (ABIN3022824, ABIN3022825, ABIN3022826 and ABIN6219246) at dilution of 1:100. (IKK alpha 抗体 (C-Term))

9 images

(3 references)

产品编号 ABIN3022825

发货至: 中国

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Quick Overview for IKK alpha 抗体 (C-Term) (ABIN3022825)

抗原

See all IKK alpha (CHUK) 抗体

IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))

适用

人

宿主

兔

克隆类型

多克隆

标记

This IKK alpha antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

抗原表位
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C-Term

序列

IWHLLKIACT QSSARSLVGS SLEGAVTPQT SAWLPPTSAE HDHSLSCVVT PQDGETSAQM IEENLNCLGH LSTIIHEANE EQGNSMMNLD WSWLTE

交叉反应

人, 小鼠, 大鼠

产品特性

Polyclonal Antibodies

纯化方法

Affinity purification

免疫原

A synthetic peptide corresponding to a sequence within amino acids 650 to the C-terminus of human IKKalpha (NP_001269.3).

亚型

IgG
anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (pSer176), (pSer177) antibody
CHUK 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (AA 646-745) antibody
CHUK 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4B8 unconjugated

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (pThr23) antibody
CHUK 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (AA 646-745) antibody
CHUK 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 1F8 unconjugated

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) antibody
CHUK 适用: 人 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 3G12H9 unconjugated

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (AA 411-745) antibody
CHUK 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (pThr23) antibody
CHUK 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) antibody
CHUK 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB2159 unconjugated

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (N-Term) antibody
CHUK 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) antibody
KD Validated CHUK 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB1065 unconjugated Recombinant Antibody

应用备注

WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200

限制

仅限研究用
状态

Liquid

缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid freeze / thaw cycles

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
Wang, Wang, Liu, Wang, Xu, Liu, Zhu, Chen, Situ, Lin: "Broadleaf Mahonia attenuates granulomatous lobular mastitis‑associated inflammation by inhibiting CCL‑5 expression in macrophages." in: International journal of molecular medicine, Vol. 41, Issue 1, pp. 340-352, (2018) (PubMed).

Gao, Yang, Yuan, Huang, Xu, Mao, Yuan, Bi: "TNFα-YAP/p65-HK2 axis mediates breast cancer cell migration." in: Oncogenesis, Vol. 6, Issue 9, pp. e383, (2017) (PubMed).

Huang, Dong, Sui, Hu, Xiong, Liao, Zhang: "MiR-223 suppresses endometrial carcinoma cells proliferation by targeting IGF-1R." in: American journal of translational research, Vol. 6, Issue 6, pp. 841-9, (2015) (PubMed).
抗原

IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))

别名

CHUK

背景

This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.,CHUK,IKBKA,IKK-alpha,IKK1,IKKA,NFKBIKA,TCF16,IKK alpha,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Phosphorylation,Signal Transduction,Kinase,Serine/threonine kinases,PI3K-Akt Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Death Receptor Signaling Pathway,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,Cardiovascular,CHUK

分子量

84 kDa

基因ID

1147

UniProt

O15111

途径

PI3K-Akt Signaling, NF-kappaB Signaling, RTK signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins