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CD11b 抗体 (AA 145-340)

Name: CD11b 抗体 (AA 145-340)
Brand: antibodies-online
SKU: ABIN3022180
Availability: OutOfStock

ITGAM 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated

Western blot analysis of extracts of various cell lines, using ITGAM antibody. (CD11b 抗体 (AA 145-340))

Immunohistochemistry of paraffin-embedded mouse spleen using CD11b/ITGAM antibody (ABIN3022179, ABIN3022180, ABIN3022181 and ABIN6218650) at dilution of 1:100 (40x lens). (CD11b 抗体 (AA 145-340))

IHC

Immunofluorescence analysis of THP-1 cells using CD11b/ITGAM Rabbit pAb (ABIN3022179, ABIN3022180, ABIN3022181 and ABIN6218650) at dilution of 1:100 (40x lens). (CD11b 抗体 (AA 145-340))

Immunohistochemistry of paraffin-embedded human tonsil using CD11b/ITGAM antibody (ABIN3022179, ABIN3022180, ABIN3022181 and ABIN6218650) at dilution of 1:100 (40x lens). (CD11b 抗体 (AA 145-340))

IHC

Immunofluorescence analysis of TF-1 cells using CD11b/ITGAM Rabbit pAb (ABIN3022179, ABIN3022180, ABIN3022181 and ABIN6218650) at dilution of 1:100 (40x lens). (CD11b 抗体 (AA 145-340))

6 images

(1 reference)

产品编号 ABIN3022180

发货至: 中国

Datasheet as PDF

抗原 See all CD11b (ITGAM) 抗体

CD11b (ITGAM) (Integrin alpha M (ITGAM))
抗原表位
16

14

10

7

6

6

5

5

4

3

3

3

3

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 145-340
适用
258

168

62

33

17

17

16

14

11

7

7

5

5

2

2

1
人
宿主
137

104

103

4

1

1
兔
Compatible Secondaries
克隆类型
251

95

1
多克隆
标记
119

37

29

26

20

10

7

6

6

6

5

5

4

4

4

4

4

4

4

3

3

3

3

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
This CD11b antibody is un-conjugated
应用范围
260

83

75

72

58

40

36

27

22

20

13

13

7

6

5

5

4

3

2

2

2

2

1

1
Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

序列

PQEDSDIAFL IDGSGSIIPH DFRRMKEFVS TVMEQLKKSK TLFSLMQYSE EFRIHFTFKE FQNNPNPRSL VKPITQLLGR THTATGIRKV VRELFNITNG ARKNAFKILV VITDGEKFGD PLGYEDVIPE ADREGVIRYV IGVGDAFRSE KSRQELNTIA SKPPRDHVFQ VNNFEALKTI QNQLREKIFA IEGTQT

交叉反应

人, 小鼠, 大鼠

产品特性

Polyclonal Antibodies

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 145-340 of CD11b/ITGAM (NP_000623.2).

亚型

IgG

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应用备注

WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

限制

仅限研究用
状态

Liquid

缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid freeze / thaw cycles

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
Wang, Zheng, Gu, Cai, Wang, Zhang, Chen, Situ, Lin, Wang: "Network-pharmacology-based validation of TAMS/CXCL-1 as key mediator of XIAOPI formula preventing breast cancer development and metastasis." in: Scientific reports, Vol. 7, Issue 1, pp. 14513, (2017) (PubMed).
抗原

CD11b (ITGAM) (Integrin alpha M (ITGAM))

别名

ITGAM (ITGAM 产品)

别名

CD11b/CD18 antibody, CR3 antibody, CR3A antibody, Cd11b antibody, F730045J24Rik antibody, Ly-40 antibody, MAC1 antibody, Mac-1 antibody, Mac-1a antibody, CD11B antibody, MAC-1 antibody, MAC1A antibody, MO1A antibody, SLEB6 antibody, C3bi antibody, integrin subunit alpha M antibody, integrin alpha M antibody, integrin, alpha M (complement component 3 receptor 3 subunit) antibody, integrin alpha-M antibody, ITGAM antibody, Itgam antibody, LOC100351865 antibody

背景

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.,CD11B,CR3A,MAC-1,MAC1A,MO1A,SLEB6,ITGAM,CD11b/ITAM,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,PI3K-Akt Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Immunology & Inflammation,CD markers,Neuroscience,Cell Type Marker,Stem Cells,Hematopoietic Progenitors,Mesenchymal Stem Cells,Microglia marker,ITGAM

分子量

127 kDa

基因ID

3684

UniProt

P11215

途径

Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation